Damanhour University

Dahono-4B: A Sovereign Foundation Model for Indonesian Legal Reasoning, Statutory Hierarchy Alignment, and Multimodal Document Intelligence

General-purpose Large Language Models (LLMs) predominantly trained on Anglo-American Common Law corpora demonstrate severe jurisdictional fragility when confronted with civil law traditions, frequently exhibiting statutory hallucination, citation of repealed legislation, and syst...

Dahono-4B: A Sovereign Foundation Model for Indonesian Legal Reasoning, Statutory Hierarchy Alignment, and Multimodal Document Intelligence

General-purpose Large Language Models (LLMs) predominantly trained on Anglo-American Common Law corpora demonstrate severe jurisdictional fragility when confronted with civil law traditions, frequently exhibiting statutory hallucination, citation of repealed legislation, and syst...

Aucubin Ameliorates Alloxan-Induced Diabetic Liver Injury in Association with Modulation of the Nrf2/HO-1 Antioxidant Axis and NF-κB-Associated Inflammatory and Apoptotic Signaling

Diabetes mellitus is associated with progressive hepatic injury driven by oxidative stress, inflammation, and apoptosis. Aucubin, a natural iridoid glycoside, possesses potent antioxidant and anti-inflammatory activities; however, its hepatoprotective mechanisms in diabetic liver...

Multivariate analysis of 110 green super rice (GSR) lines for morpho-physiological diversity attributes

Genetic diversity present in rice genotypes plays a crucial role in improving breeding strategies and developing high-quality cultivars. This study evaluated genetic diversity, agronomic performance, and disease resistance across 110 unique rice cultivars over two growing seasons...

Epigenetic Regulation of Host Immunity During Parasitic Infections: Mechanisms, Immune Evasion, and Therapeutic Opportunities

INTRODUCTION: Parasitic infections remain a major global health challenge involving complex interactions between pathogens and host immunity. Emerging evidence indicates that epigenetic mechanisms, including DNA methylation, histone modifications, chromatin remodeling, and non-co...

Biogenic synthesis and characterization of selenium nanoparticles by halotolerant Bacillus sonorensis 2MNHR

Abstract Selenium nanoparticles (SeNPs) have attracted significant attention owing to their unique physicochemical properties and promising biomedical applications. In the present study, a newly isolated halotolerant marine Bacillus sonorensis 2MNHR strain was employed for the ex...

Growth-promoting influence of selenium nanoparticles and ulvan derived from Ulva lactuca on the growth of maize during the seedling stage

Abstract Marine algae contain a vast array of bioactive molecules with diverse uses. One of their interests is to apply seaweed-derived nanoparticles or polysaccharides as bio-stimulants of seed germination for plant growth promotion. Two products derived from the green alga Ulva...

CD38 Inhibition Enhances FXR Signaling in Male Rats With Diabetic Steatohepatitis Through SIRT1‐Dependent Suppression of NLRP3

ABSTRACT Diabetic steatohepatitis, now clinically framed within metabolic dysfunction‐associated steatohepatitis (MASH), features progressive disruption of hepatic microarchitecture alongside sterile inflammatory microdomains. Farnesoid X receptor (FXR) activity is restrained by...

Can Carica papaya Serve as an Adjunct to Semaglutide in Mitigating Diabetes-Induced Testicular Injury Through Modulation of Oxidative Stress, Inflammation, Apoptosis, and the miR-34c/miR-155–SIRT1/FOXO1 Axis? An Experimental and Chem-Bio-Informatics Study

Diabetes mellitus (DM) induces significant endocrine disruption and oxidative stress (OS) within the testes, resulting in impaired spermatogenesis, increased sperm abnormalities, and compromised reproductive function. This study aimed to evaluate the combined protective effects o...