Dali University

Microclimatic effects on activity patterns in a montane chimpanzee population

Abstract Climatic variation can shape primate activity budgets by altering the energetic and thermoregulatory costs of feeding, resting, locomotion and social behaviour. However, little is known about how chimpanzees that inhabit cool, wet montane forests adjust their activity in...

Factors affecting the decline of intrinsic capacity of older adults in Chinese communities: a systematic review and meta-analysis

With the rapid aging of the global population, maintaining the intrinsic capacity of older adults has become a critical public health priority. However, the pooled prevalence of intrinsic capacity decline and its key determinants remain unclear. This study aims to assess the rate...

Integrated Transcriptomic and Proteomic Analyses Reveal a Diverse Venom Repertoire in Macrothele guizhouensis

Abstract The venom of spiders in the family Macrothelidae is a rich source of bioactive molecules with potential biomedical and agricultural applications, yet the venom composition of Macrothele guizhouensis remains poorly understood. Here, integrated transcriptomic and proteomic...

Emerging roles of long non-coding RNA CASC2 in tumor chemoresistance – a review

Malignant tumors remain a leading cause of global mortality, and the development of chemoresistance represents a major obstacle to effective cancer treatment. Long non-coding RNAs (lncRNAs) are important regulators of tumor progression and therapeutic response. Cancer susceptibil...

Post-marketing safety assessment of tetrandrine based on the WHO-VigiAccess database

Tetrandrine, a bisbenzylisoquinoline alkaloid extracted from Stephania tetrandra S. Moore, is clinically used in the treatment of silicosis and rheumatoid arthritis. Despite its demonstrated efficacy, systematic safety evaluations remain limited. This study represents the first e...

Differences in weight loss practices and perceptions between medalists and non-medalists in national-level adolescent Sanda athletes

Objectives This study aimed to compare weight loss (WL) practices and perceptions between medalists and non-medalists among Chinese national-level adolescent Sanda athletes. Methods A cross-sectional survey was conducted among national-level adolescent Sanda athletes using the Ra...

Construction of LaFe0.5Ni0.5O3/g-C3N4 S-scheme heterojunction for dramatically enhanced photocarrier separation toward efficient photocatalytic deodorization of livestock wastewater: Based on in-situ irradiation XPS and fs-TAS analysis techniques

Odor emissions from livestock and poultry farms have become an urgent environmental challenge and a scientific concern. Indole is one of the predominant malodorous compounds responsible for this issue. To explore effective deodorization strategies, indole was selected as a model...

Integrated management strategies for sustainable intensification of a sweet maize–vegetable triple-cropping system in a water-sensitive region

Context and objective Intensive sweet maize–vegetable cropping systems are critical for food production but typically rely on excessive nutrient inputs, leading to substantial nitrogen (N) and phosphorus (P) losses, particularly in water-sensitive regions. However, most field stu...

Comparative chloroplast genomics of Ajania sericea and sympatric Asteraceae species identifies shared candidate molecular features associated with alpine adaptation

Ajania sericea is endemic to the Dali region of Yunnan and is currently the southernmost known member of the genus Ajania worldwide. It co-occurs with Aster brachytrichus , Anaphalis pannosa , and Leontopodium dedekensii in alpine habitats of northwestern Yunnan, where plants are...

Iron Single-Atom Catalyst Boosting Dried Blood Spots Digestion for High-Throughput Detection of Arsenic and Cadmium

Abstract Herein, a novel Fenton-like digestion strategy has been developed for undiluted, rapid, and high-throughput digestion of DBS samples. The key of this strategy is the development of a blood collection card loaded with iron single-atom catalysts (Fe-SACs). Then, approximat...

Lattice Mismatch-Directed Construction of Cu−Co Interfaces for CO2 Hydrogenation to C2+ Alcohols

Abstract Cu−Co bimetallic catalysts have demonstrated considerable potential for CO2 hydrogenation to C2+ alcohols. However, their practical application remains constrained by excessive CH4 formation arising from the uncontrolled reduction of Co species under reaction conditions....

Genome-Wide Identification of the CmABF Gene Family in Melon (Cucumis melo L.) and Their Response to Ozone and ABA

Melon (Cucumis melo L.) is a globally significant horticultural crop whose fruit quality and postharvest shelf life are profoundly influenced by oxidative stress. Abscisic acid (ABA)-responsive element binding factors (ABFs), which represent the Group A subfamily of the basic leu...

Liver cancer stem cells drive hepatocellular carcinoma progression and therapeutic resistance

Hepatocellular carcinoma (HCC) is a highly prevalent and lethal malignancy worldwide, with persistently high rates of therapeutic resistance and post-treatment recurrence. Liver cancer stem cells (LCSCs), a distinct subpopulation of cancer cells endowed with stem cell-like proper...

Agonist Binding Reshapes the Kinetic Landscape and Allosteric Communication of APLNR Toward Activation-Competent States

APLNR is a therapeutically important G protein-coupled receptor (GPCR) implicated in cardiovascular and metabolic regulation; however, how agonist binding reorganizes receptor dynamics to promote signaling competence remains poorly understood. Here, we used the small-molecule ago...

Salt-tolerant β-glucosidases from Karamay saline soil for soybean isoflavone bioconversion

β-Glucosidase (EC 3.2.1.21) hydrolyzes β-glycosidic bonds and is widely used in the food, fuel, and pharmaceutical industries. It holds significant potential particularly for converting glycosides, such as soybean isoflavone glycosides and ginsenosides, into their more bioactive...

Exploration and practice of a DeepSeek‑enhanced, scenario‑based teaching model integrated with a multidisciplinary team approach in gastroenterology residency training

The first year of standardised residency training is a critical transition from medical student to clinical practitioner, during which trainees struggle to integrate theoretical knowledge with clinical competencies. Traditional teaching often lacks active learning and authentic c...

Machine learning–guided identification of determinants of PD-L1 expression and tumor mutational burden in lung squamous cell carcinoma

Programmed death-ligand 1 (PD-L1) expression and tumor mutational burden (TMB) are widely used immunotherapy biomarkers, yet their variability and determinants in lung squamous cell carcinoma (LUSC) remain incompletely characterized in real-world testing settings. We analyzed a r...