Dali Traditional Chinese Medicine Hospital

Magnoflorine Ameliorates Metabolic Dysfunction-Associated Steatotic Liver Disease by Targeting the NDUFV1 Subunit of Complex I to Regulate the ROS/AMPK Signaling Pathway

Abstract Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent metabolic disorder with limited therapeutics. Magnoflorine (MAG), a natural alkaloid from edible plants, ameliorates MASLD; however, its direct targets remain unclear. Here, by integrating th...

Redistribution of CD73 Expression on CD4+T Subpopulations in Systemic Lupus Erythematosus and Its Association With Disease Activity

ABSTRACT Systemic lupus erythematosus (SLE) is a complex autoimmune disorder driven by aberrant immune responses, predominately CD4 + T cells dysfunction. CD73, an ecto‐5′‐nucleotidase mediating adenosine signalling, is essential for immune regulation. Herein, we investigated CD7...