Dalhousie University

P1.173. Endoscopic Resection Versus Esophagectomy for T1b Esophageal Cancer – a Systematic Review and Meta-Analysis

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer Background Esophagectomy remains the standard of care for most esophageal cancer. Newer evidence supports the use of endoscopic resection (ER) including endoscopic mucosal resection (EMR) or endoscopic subm...

Costs and benefits of group size for sperm whales of the open ocean

Abstract Individual feeding success can change with the size of a social group through competition, cooperation, recruitment and other processes. Female sperm whales (Physeter macrocephalus) live in long-term social units that themselves can form larger, temporary groups, but the...

“As soon as it’s trying to be persuasive, my skepticism kicks in”: A qualitative study to co-design vaccine communication strategies with vaccine hesitant adults in Canada

Vaccine hesitancy continues to impede vaccine uptake in Canada. Few interventions directly engage hesitant adults in co-designing communication materials. This study aimed to co-develop and evaluate digital vaccine communication messages with hesitant adults in Canada to improve...

“I know how important it is”: A qualitative analysis of participants’ experiences in a vaccine safety study

Specialist immunization clinics can support vaccination counseling for individuals experiencing adverse events following immunization (AEFIs) and research into AEFIs. We sought to describe the experiences of participants from the Canadian Special Immunization Clinic Network COVID...

Dr. Tsai et al reply

We appreciate the interest of Drs. Wang and Qu¹ in our work,² and their call for more family-friendly metrics to help convey meaningful quality of life improvements in juvenile idiopathic arthritis ( JIA). After considering the different ideas suggested in t...

How to Train Your Chatbot: Information‐Theoretic Foundations of Diagnostic Questioning in Inborn Errors of Immunity

BACKGROUND: Navigating the more than 550 inborn errors of immunity (IEI) requires efficient diagnostic reasoning. Information theory suggests questions should be prioritized by their capacity to reduce diagnostic uncertainty (entropy); yet whether experts or large language models...

Feasibility, Acceptability and Outcomes of Group CBT ‐T: A Naturalistic Mixed‐Methods Comparison With Individual CBT ‐T

ABSTRACT Objective This study aimed to evaluate the feasibility of implementing 10‐session group cognitive behavioural therapy (CBT‐Tg) in routine outpatient eating disorder care and to descriptively examine outcomes of CBT‐Tg and individual CBT‐T (CBT‐Ti). Method Using a natural...

Characterization of Sec14 Domain–Containing Proteins in the Malaria Parasite Plasmodium falciparum

ABSTRACT Plasmodium falciparum parasites cause the most virulent form of malaria, a disease that remains a major global health burden. The appearance of resistance to first line artemisinin‐based therapies emphasizes the need to identify new parasite vulnerabilities to develop ne...

Resilience and Protective Factors for Mental Health among Indigenous Youth in Canada: A Scoping Review

Abstract Indigenous youth’s inherent strength and resilience play a vital role in their well-being and mental health. Protective factors, closely linked to resilience, spanning individual, family, and community levels reinforce positive mental health outcomes. The purpose of the...

Lamotrigine and other therapy-associated HLH syndromes: a review

INTRODUCTION: Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of pathologic immune activation that can occur secondary to medical interventions including immunomodulatory therapies such as immune checkpoint inhibitors and stem cell transplantation. However, lamotrigine and...

“We Were in Solidarity with Each Other”: Oral Histories on Coming Out During the AIDS Crisis in Canada

This paper explores identifying, "coming out" and "coming in" as Two Spirit, lesbian, gay, bisexual, trans, and/or queer (2SLGBTQ+) during the AIDS crisis in Canada (1981-1997). We conducted 30 oral history interviews about this unique historical moment between 2022 and 2025 with...

Self-Assembled Monolayersof Phosphorus–NitrogenCages

Abstract This study investigates the deposition of the phosphorus–nitrogen (PN) cage P2N6 onto Au and Cu surfaces using both vapor-phase and solution-phase methods. The P2N6 cage sublimes cleanly and reaches an onset of volatility near 83 °C, suitable for vapor-phase deposition p...

Growth efficiencies of essential fatty acids vary with dietary concentration in Atlantic Pollock (Pollachius virens)

The essential fatty acids (EFA) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are required for the maintenance of good health in humans. In the marine environment, they are primarily synthesized by phytoplankton and their production is predicted to decrease with warm...

The value of electronic tagging and tracking studies for understanding fish–hypoxia interactions

Abstract Objective Hypoxia (i.e., low dissolved oxygen availability) is a natural phenomenon but can also be induced by human activities (e.g., nutrient enrichment from runoff). Given that dissolved oxygen is essential for aquatic life, periods of hypoxia tend to have negative co...

A Novel Approach to Characterizing Patterns of Real-World Upper-Extremity Use During Walking and Activities of Daily Living in People with Subacute Stroke

In accelerometer-based measurement, the inclusion of upper extremity (UE) activity during walking can overestimate real-world functional UE use in people post-stroke. This study introduces a comprehensive, accelerometer-based approach to examining real-world UE use, including the...

Integrating is success and open innovation in enterprise LLM adoption: a dual-path model of net benefits and usage growth

Firms are increasingly adopting Large Language Models (LLMs) to enhance productivity and eventually save costs and increase revenue. Continued LLM adoption requires that LLMs demonstrate tangible Return-on-Investment, making it essential to verify whether cost reductions and reve...

Confirming the Factor Structure, Concurrent Validity, and Testing the Measurement Invariance Across Gender and Sexual Orientation for the Process-Based Consent Scale

The Process-Based Consent Scale (PBCS) was developed to reflect contemporary consent attitudes and practices, with three subscales (Ongoing Consent, Subtle Coercion, and Communicative Sexuality) emerging through exploratory and confirmatory factor analysis. However, its measureme...

Management of Pre-Existing Inflammatory Arthritis During Immune Checkpoint Inhibitor Therapy for Metastatic Renal Cell Cancer with a TNF Inhibitor for over 6 Years: A Case Report

Background The use of immune checkpoint inhibitors (ICIs) has transformed cancer care by using the body’s own immune system to target malignant cells. ICIs can cause unintended off-target effects, termed immune related adverse events (irAEs), which can be de novo or related to pr...

Evaluating Frailty in Systemic Lupus Erythematosus: A Scoping Review

Objectives There is growing interest in using frailty to better understand the heterogeneous health outcomes observed among people living with systemic lupus erythematosus (SLE). This scoping review aimed to 1) Identify and describe the tools and measures used to characterize fra...

Telephone versus in-person administration of the Early Childhood Development Index 2030: a crossover study, Brazil, Canada, India and Malawi.

Objective: To examine agreement between telephone and in-person administration of the Early Childhood Development Index 2030 (ECDI2030) survey. Methods: -tests and intraclass correlation coefficients. Findings: : -0.36), regardless of modality. However, pooled and stratified intr...