Cystic Fibrosis Research Foundation

Influence of flow-type-dependent matrix rheology on droplet breakup in twin-screw extruded polymer blends

Abstract The morphology of immiscible polymer blends generated during twin-screw extrusion depends on the deformation history of the dispersed phase and on the matrix rheology. Here, this effect is investigated numerically in a two-dimensional, co-rotating, fully intermeshing bat...

T cell–intrinsic AIM2 exacerbates lung inflammation in OVA-LPS- and HDM-induced asthma models

Asthma is a heterogeneous inflammatory airway disease characterized by immune dysregulation, airway hyperresponsiveness (AHR), and excessive immune activation. Although NLRP3 (NOD-like receptor family pyrin domain-containing 3) has been extensively studied in asthma, its role rem...