Corewell Health

Databases, registries, and consortia for pediatric epilepsy and functional neurosurgery: a scoping review from the AANS/CNS Pediatric Section Epilepsy and Functional Research Interest Group

OBJECTIVE The practice of pediatric epilepsy and functional neurosurgery relies on high-quality data systems to advance clinical care, evaluate outcomes, and develop evidence. Despite the importance of multicenter research in supporting these goals, no consolidated inventory exis...

Trial-related informational needs and decision-making in the SMA community after broad treatment access: results of the 2nd Cure SMA clinical trial experience survey

Abstract Background When clinical trials were the only avenue for people with spinal muscular atrophy (SMA) to access potentially effective disease-modifying therapies (DMTs), people often traveled long distances for trials and were willing to tolerate significant treatment-relat...

Complementary vertebrate Wac models exhibit phenotypes relevant to DeSanto-Shinawi Syndrome

Monogenic syndromes are associated with neurodevelopmental changes that result in cognitive impairments and neurobehavioral phenotypes, including autism and seizures. Limited studies and resources are available to make meaningful headway into the underlying molecular mechanisms t...

Artificial intelligence in electrocardiogram interpretation for cardiovascular diagnosis and risk prediction: a systematic review of evidence through May 2026

Abstract Background Artificial intelligence-enabled electrocardiogram (ECG) analysis has expanded across cardiovascular diagnosis, monitoring, and risk prediction, but published studies vary in methodology, validation, and clinical applicability. We systematically reviewed AI app...