Connecticut Children's Medical Center

A “Suture Staple” Knotless Anchor Technique for Fixation of Tibial Tubercle Avulsion Fractures in Pediatric Patients

Abstract Tibial tubercle fractures are rare injuries most commonly seen in the pediatric population; more specifically the adolescent male population towards the end of peak longitudinal growth. Typically, tibial tubercle fractures are fixed with cannulated screws. However, there...

Fecal microbiome transplant in food allergy in humans and mice identifies a role for bile acid metabolites in oral tolerance

The gut microbiome has been implicated in the pathogenesis of food allergy (FA), prompting microbiome-focused interventions. We evaluated, in a phase 1 open-label trial (NCT02960074), the safety and efficacy of oral encapsulated fecal microbiome transplantation (FMT) in 15 adults...