Community Health Center

A nomogram for predicting the risk of incident LDL-C elevation in type 2 diabetes mellitus: development and external validation in a community-based cohort

Dyslipidemia is a major risk factor for cardiovascular complications in patients with type 2 diabetes mellitus (T2DM), and early risk assessment may help inform follow-up and lipid monitoring. This study aimed to develop and externally validate a nomogram based on Cox proportiona...

Barriers and facilitators to home-based osteoporosis self-management among older lung transplant recipients: a qualitative study

Osteoporosis is common after lung transplantation and is a particular concern in older recipients. It is associated with increased risks of fracture, frailty, disability, and hospital readmission and may compromise functional recovery. After discharge, recipients need to sustain...

Effect of Dyadic Care Types on Knowledge‐Attitude‐Practice Relationship in Coronary Heart Disease Caring Dyads: A Moderated Mediation Model

ABSTRACT This study aimed to validate the knowledge‐attitude‐practice (KAP) model in coronary heart disease (CHD) patients and their family caregivers, and examine the moderating role of dyadic care types. Data were collected from 281 patient‐caregiver dyads, and moderated mediat...

Association between eye movement behavioral indicators and plasma p-tau217

Alzheimer’s disease (AD) represents a growing global public health burden driven by progressive population aging. Early identification of AD-related pathological alterations is essential for timely intervention and risk stratification; however, currently available screening appro...

Toxicities of cancer immunotherapy: clinical manifestations, underlying mechanisms, and management

Abstract Cancer immunotherapy, particularly immune checkpoint inhibitors (ICIs) and chimeric antigen receptor T-cell (CAR-T) therapy, has transformed the treatment landscape of multiple malignancies. However, dysregulated immune activation can cause a wide range of toxicities tha...

A practical nomogram for the early prediction of hemiplegic shoulder pain in stroke patients: a development and validation study

Abstract Objective To facilitate early clinical risk stratification for hemiplegic shoulder pain (HSP) after stroke, this study aimed to identify potential risk factors and develop a predictive nomogram. Methods This retrospective study included 450 inpatients with stroke admitte...

Early Emergence of Cultural Differences in Audiovisual Speech Perception

Integrating auditory and visual cues is a hallmark of human speech perception, yet adults from East Asian backgrounds show less reliance on visual speech than their Western counterparts. The origins of this cultural difference, however, remain unknown. To investigate whether this...

Integrated multi-omics analysis identifies AKR1B15 and SLC4A10 as prognostic candidate citrullination-related genes associated with metabolic and immune programs in hepatocellular carcinoma

Protein citrullination has been increasingly implicated in tumor progression and immune regulation, but the prognostic and cellular characteristics of citrullination-related genes (CRGs) in hepatocellular carcinoma (HCC) remain incompletely understood. We integrated bulk transcri...

Serum metabolomic profiling reveals lipid remodeling and energy metabolic dysregulation in myocardial infarction

Myocardial infarction (MI) is accompanied by profound metabolic remodeling, yet the integrated circulating metabolic phenotype remains incompletely defined. Objective: We performed untargeted serum metabolomics to identify the coordinated metabolic signature of MI. Results: A tot...

Medical students’ awareness and beliefs regarding third-hand smoke

Third-hand smoke refers to residual tobacco smoke contaminants that persist on indoor surfaces, dust, clothing, hair, and skin after smoking has ceased. This study assessed medical students’ prior awareness, perceived knowledge, and beliefs regarding third-hand smoke-related heal...

Implementation Experiences From the Community Health Workers for COVID Response and Resilient Communities Initiative.

. 2026;116(S4):S272-S275. https://doi.org/10.2105/AJPH.2026.308714).

Assessing Public Health and Preventative Health Needs of Underserved Communities in Rhode Island.

BACKGROUND: In the United States, significant disparities exist in preventative health among underserved communities, including African American/Black (AA/B), Hispanic/Latino (H/L) and lesbian/gay/bisexual/transgender/ queer (LGBTQ+) individuals. We explored the influence of soci...

Latent Profile Analysis of Childhood Trauma and Loneliness Among Community-Dwelling Older Adults and Their Association with Depressive Symptoms

BACKGROUND: Depression is a leading mental health concern among community dwelling older adults, with childhood trauma and current loneliness identified as critical risk factors. However, existing research has predominantly examined these variables in isolation, obscuring heterog...

Ultrasound-assisted glycyrrhetinic acid/nitric oxide co-loaded albumin nanoparticles for the synergistic treatment of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is widely recognized as one of the three leading causes of cancer-related death worldwide. Glycyrrhetinic acid (GA) exhibits potent anti-HCC activity, but its poor aqueous solubility limits its clinical application. At high concentrations, nitric ox...

A Therapeutic Greenhouse Model for School‐Based Health

ABSTRACT Background The Therapeutic Greenhouse Program, located at an elementary school in an underserved community, offers a sustainable and reproducible model for school‐based garden programming. Developed by a school‐based health center, the program integrates medical and beha...

Palliative care knowledge and attitudes toward end-of-life care among clinical nurses across healthcare settings in Guangzhou, China: a cross-sectional study

Despite growing global recognition of palliative care’s importance, access to adequately trained professionals and high-quality services remains highly unequal across countries. Nurses’ knowledge and attitudes are critical determinants of end-of-life care quality, yet evidence fr...

Latent subtypes and gender differences in the comorbidity of depression and sleep disturbances among adolescents: insights from network analysis and latent profile analysis

This study aimed to explore potential subtypes, influencing factors, and gender differences in the associations between adolescent depression and sleep disorders. A cross-sectional study was conducted among adolescents utilizing the Center for Epidemiologic Studies Depression Sca...

Embedded Fishbone Foreign Bodies in the Tongue: Clinical Characteristics and Treatment Strategies: A Retrospective Study

BACKGROUND: Lingual fishbone foreign bodies completely embedded in the deep lingual musculature present significant surgical challenges due to imprecise preoperative localization and the risk of iatrogenic injury to neurovascular structures. However, the current literature on thi...

Derivation of a novel risk assessment model of venous thromboembolism in hospitalized patients

Background Venous thromboembolism (VTE), which includes deep vein thrombosis (DVT) and pulmonary embolism (PE), significantly contributes to morbidity and mortality among hospitalized patients. Despite the existence of various VTE risk assessment models (RAMs), their performance...