Coimbatore Medical College and Hospital

EVOLUTION OF COMPUTER-AIDED DRUG DESIGN: EMERGING TECHNOLOGIES AND FUTURE OPPORTUNITIES IN DRUG DISCOVERY

AbstractBackground: The process of drug discovery and development is complex and costly, withincreasing expenses and extended timelines. Computer-Aided Drug Design [CADD] hasemerged as a transformative approach to address these challenges, leveraging computationalmethods to strea...

Measurement, meaning and the limits of research methods in mental health: a case for methodological pluralism

Purpose This paper explores the limits of current research methods in mental health. Quantitative methods are useful for diagnosis, measurement and treatment outcomes, but they do not fully capture patient experience, meaning and cultural context. The aim of this study is to high...

Pilot validation of a piezo‑resistive gnathodynamometer for maximum voluntary bite force measurement in adults: a cross sectional comparative study

Maximum voluntary bite force (MVBF) is a key indicator of masticatory system function, influenced by cranio-mandibular biomechanics, neuromuscular coordination, and dental status. Conventional bite force devices, though widely used, are limited by their bulk and potential discomf...