CMH Lahore Medical College and Institute of Dentistry

Cardiovascular outcomes associated With GLP-1 and dual GLP-1/GIP receptor agonists in patients with type 2 diabetes and inflammatory bowel disease: A retrospective real-world cohort study

Introduction Individuals with co-morbid T2D and IBD represent a uniquely high-risk group, facing amplified cardiovascular risk through synergistic inflammatory and metabolic pathways, in whom conventional cardiometabolic strategies (such as dietary and lifestyle changes, weight l...

Anesthetic Approaches for Left Atrial Appendage Occlusion: Comparing Conscious Sedation and General Anesthesia: A Meta Analysis

Background Left atrial appendage occlusion (LAAO) offers a mechanical alternative to anticoagulation for stroke prevention in nonvalvular atrial fibrillation patients. However, the optimal anesthetic strategy—general anesthesia (GA) versus conscious sedation (CS)—during LAAO rema...

Efficacy and Safety of Savolitinib Plus Osimertinib in EGFR-Mutant, MET-Aberrant Advanced Non–Small Cell Lung Cancer

Objectives: NSCLC is the leading cause of cancer-related mortality. While combined therapy including savolitinib and osimertinib appears promising, there exists a lack of comprehensive pooled evidence regarding its anti-oncological activity. : The objective of this study is to ev...

Evaluation of a community-based education program on maternal and child health needs in a semi-urban locality: a university-community partnership pilot project in Lahore, Pakistan

Pakistan faces high maternal and child mortality rates, with semi-urban and rural areas particularly affected. Community-based initiatives that emphasize local participation can address these challenges by fostering community ownership and sustainability. This study evaluated a c...

Efficacy of rituximab plus lenalidomide regimens in follicular lymphoma: a meta-analysis of randomized controlled trials

Follicular lymphoma (FL) is an incurable, indolent non-Hodgkin lymphoma with a high relapse rate despite effective chemoimmunotherapy. Lenalidomide, an immunomodulatory agent, in combination with rituximab (R²), has been evaluated as an alternative to chemoimmunotherapy and to ot...

A narrative review of Zika virus cardiotropism and atrial fibrillation from pathogenesis and diagnostic challenges to inflammation aware management

Systemic inflammation is a key driver of atrial fibrillation (AF), but the mechanisms linking specific viral triggers to arrhythmogenesis are not fully understood. Zika virus (ZIKV) infection, which can induce a significant inflammatory response, provides a compelling clinical mo...

Ghost (virtual) ileostomy compared with protective ileostomy after low anterior resection for rectal cancer: A GRADE-assessed systematic review and meta-analysis

Protective ileostomy is commonly performed after low anterior resection for rectal cancer to mitigate the clinical consequences of anastomotic leakage; however, it is associated with stoma-related and reversal-related morbidity. Ghost ileostomy has emerged as a selective alternat...

Ropeginterferon alfa-2b in Polycythemia Vera: A systematic review and meta-analysis

Background: Ropeginterferon alfa-2b, a novel monopegylated interferon with improved pharmacokinetics, has emerged as a promising cytoreductive agent for managing polycythemia vera (PV). Despite increasing adoption, evidence synthesis of its efficacy and safety compared to standar...