Clínica Las Condes

PEEK Pectus Bar: Evaluation of a New Material for Pectus Excavatum Repair in Children and Teenagers

The Nuss procedure for Pectus Excavatum repair has relied on metallic bars for the past 3 decades. The technical efforts have focused on the improvement of stability and the reduction of the associated risks. However, some challenges still remain, like metal ion release, thoracic...

Alveolar bone loss and dentoalveolar remodelling in pre-Columbian human remains from northern Chile

Alveolar bone loss in archaeological human remains is a composite skeletal outcome influenced by biological ageing, occlusal function, compensatory eruption, antemortem tooth loss, and inflammatory destruction. Accordingly, cementoenamel junction–alveolar crest (CEJ–AC) distance...

Mapping early PRC2 nucleation sites upon Suz12 reintroduction reveals features of de novo Polycomb recruitment

Polycomb domains safeguard cell identity by maintaining lineage-specific chromatin states enriched in repressive histone modifications, preserving the epigenetic memory of cell lineages. While Polycomb repressive complex 2 (PRC2) can reestablish its occupancy after perturbation,...

Interlaminar Contralateral Endoscopic Foraminotomy Reduces Postoperative Dysesthesia in Patients With Degenerative Lumbar Deformity: A Multicenter Comparative Cohort Study

Study Design Retrospective-prospective multicenter comparative cohort study. Objectives Postoperative dysesthesia (POD) is a recognized complication of transforaminal endoscopic lumbar surgery, with reported rates up to 21.5%. Degenerative lumbar deformity may amplify this risk t...

Surgical anatomy, biomechanics and clinical outcomes of latissimus dorsi transfer for irreparable rotator cuff tears: a review

BACKGROUND: Latissimus dorsi transfer is a well-established joint-preserving option for irreparable rotator cuff tears in young, active patients without glenohumeral arthritis. Originally described by Gerber in 1988 for posterosuperior tears, indications now also include anterosu...

Impact of Spatial Knowledge on Fire Evacuation Performance in Large Buildings: An Integrated Simulation Approach

This study examines human evacuation performance in complex building environments under highly uncertain fire conditions, with a focus on how spatial knowledge and decision-making strategies influence exposure to hazardous conditions during emergencies in smart building contexts....