Cleveland Eye Clinic

Outer Retinal Volume on Macular OCT Predicts Two-Year Diabetic Retinopathy Progression

Purpose: To evaluate whether baseline retinal volume from macular optical coherence tomography (OCT) is associated with diabetic retinopathy (DR) progression over two years. Methods: In this longitudinal observational study, 190 eyes from 121 patients, across the DR severity spec...

Deep Brain Stimulation: A Window Into the Neural Mechanisms of Latent Nystagmus

Purpose: Latent nystagmus is a condition marked by a nasal-ward drift of the eye that reverses depending on the fixating eye. It is commonly associated with early-onset strabismus and amblyopia and is hypothesized to result from disrupted horizontal binocular connections in the p...

A comparative meta-analysis of amniotic membrane preservation methods: Balancing biological potency and clinical feasibility in ophthalmology

Objectives: The objective of the study is to systematically compare biological and structural properties of fresh, cryopreserved, lyophilized, and dehydrated human amniotic membrane (AM) and to quantify sufficiently comparable outcomes across preservation methods. Material and Me...

Neuroprotective effects of ketamine, lamotrigine, and ketoprofen combinations after pars plana vitrectomy and silicone oil injection

Abstract Purpose This experimental study aims to assess the protective impact of combined treatment with ketamine (KTM), lamotrigine (LMT), and ketoprofen (KTP), agents that have demonstrated neuroprotective properties in other experimental contexts, on rabbit retinas in an exper...