City of Scientific Research and Technological Applications

In Ovo Folic Acid Injection Modulates Hatchability, Hematobiochemical Profiles, Immune Status, and Intestinal Histomorphology of Day-Old Broiler Chicks

This study evaluated the effects of in ovo folic acid administration on hatchability, physiological profiles, and intestinal development in day-old Cobb broiler chicks. A total of 600 embryonated eggs were assigned to five treatments: an uninjected control, a saline control, and...

Green-synthesized copper nanoparticles differentially modulate germination and selected stress-response genes in Phelipanche aegyptiaca

Abstract Egyptian broomrape ( Phelipanche aegyptiaca ) is a devastating parasitic weed requiring eco-friendly control strategies. This in vitro study investigated the effects of green-synthesised copper oxide (CuO) nanoparticles, produced using Anethum graveolens extract, on P. a...

Insecticidal activity of Metarhizium anisopliae-mediated nanoparticles and fungal metabolites against the red palm weevil, Rhynchophorus ferrugineus

Abstract This study evaluated the insecticidal activity of green-synthesized metallic nanoparticles (Ag, CuO, and ZnO) and the ethanolic extract of Metarhizium anisopliae against the red palm weevil ( Rhynchophorus ferrugineus ). Physicochemical characterization confirmed the suc...

Serum HDGFL2 as a novel biomarker for disease activity in Egyptian patients with rheumatoid arthritis

Abstract Background Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder characterized by persistent joint inflammation and tissue damage. The pathogenesis of RA involves complex immune dysregulation, necessitating the identification of reliable biomarkers to a...

Synthesis and in silico studies of hexahydroacridine derivatives as potential antitumor agents

Abstract Despite advances in targeted cancer therapies, drug resistance and off-target toxicity remain major challenges, underscoring the need for new multi-targeted agents with improved selectivity. The present study evaluated the anticancer potential of newly synthesized hexahy...

Analysis of reproductive behavior in male pigeons in the White Mirthys and Egyptian Baladi breeds injected with testosterone propionate

Abstract Background In pigeons, reproductive success is driven primarily by male courtship and copulatory behavior, both of which require threshold levels of circulating testosterone. This study investigated the effects of exogenous testosterone propionate (TP) injection on serum...

Assessing the potential, effectiveness and implementation challenges of beach and tourism ecolabels for beach macrolitter reduction

Abstract There is an urgent need to address the contribution of mass tourism to coastal litter generation, however, identifying effective, context-specific measures to reduce listed litter remains challenging. This study evaluated 142 beach and tourism ecolabels against a list of...

Machine learning-based prediction of SARS-CoV-2 bioactivity: integrating IC50 regression and activity classification using multi-task neural networks

Abstract Accurate prediction of compound bioactivity is essential for accelerating antiviral drug discovery and reducing experimental costs. Machine learning (ML) methods have shown considerable promise in modeling structure–activity relationships and compound potency. In this st...