Chuxiong Normal University

High‐Resolution Temperature and Precipitation Variability in Northeast Asia Since the Last Glacial Maximum Recorded in an Annually Laminated Maar Lake

Abstract Temperature and precipitation variability in monsoonal Asia is central to understanding regional climate dynamics and global teleconnections. How post‐LGM warming and hydroclimate change unfolded in Northeast Asia, and how they were linked to external forcing, remain poo...

Nano-modified biochar mitigates toxicity from co-contamination with lead and microplastics in alfalfa by modulating photosynthesis, nitrogen assimilation, and antioxidant systems

Microplastics (MPs) and heavy metals are released into the environment and pose serious challenges to crop productivity and human health. The role of biochar and calcium oxide nanoparticle (CaO-NPs) modified (NBC) in mitigating MPs and lead (Pb 2+ ) toxicity has not yet been expl...

Research progress on the diagnosis and treatment of far-out syndrome

Abstract Far-out syndrome (FOS) is a rare cause of L5 radiculopathy, resulting from extraforaminal compression of the L5 spinal nerve within the lumbosacral tunnel. The diagnosis requires the simultaneous fulfillment of two necessary conditions: compression located within this sp...

Handwritten Dictionary Retrieval for Digital Access to Yi Script Heritage

Abstract Traditional Yi script preserves linguistic knowledge and cultural memory, yet dictionary access can be difficult when users can visually recognize or reproduce a glyph but do not know its pronunciation, encoding, or index. We present a handwriting-based retrieval framewo...

Targeted agents combined with immune checkpoint inhibitors in advanced non-small cell lung cancer: a systematic review and externally anchored Bayesian network meta-analysis

Targeted agents combined with PD-1 or PD-L1 blockade have been investigated in advanced non-small cell lung cancer (NSCLC), but the evidence is dominated by small single-arm studies in clinically distinct populations. We evaluated class-level activity, safety, and progression-fre...

Sphallerocarpus gracilis Polyphenols Alleviate DSS-Induced Colitis by Remodeling Gut Microbiota and Inhibiting the AGE-RAGE/HMGB1 Pathway

As a traditional Tibetan medicine and health food, the fleshy roots of Sphallerocarpus gracilis were adopted to extract polyphenol powder(PP) in this research. Using a DSS-induced colitis mouse model combined with multi-omics analysis and experimental validation, we explored the...

Psychological effects of temporal landmarks: A meta-analysis of affective, cognitive, and self-regulatory processes

Temporal landmarks, distinct time points that may shape affect, cognition, and self-regulatory behavior, have effects whose magnitude and boundaries remain uncertain. This meta-analysis systematically synthesized findings on the psychological outcomes linked to temporal landmarks...

Acupuncture alleviates the progression of lumbar disc herniation by regulating the autophagy level of nucleus pulposus cells through the SIRT1/Sestrin2 pathway.

BACKGROUND AND PURPOSE: Lumbar disc herniation (LDH) is a degenerative spine disease and the most common cause of lower back pain, with a high prevalence in younger patients. The use of acupuncture (AC) as a conservative treatment for LDH has received widespread attention at home...

Development of a nomogram for predicting extramural venous invasion in colon cancer using spectral CT multiparameter imaging

Abstract Purpose To develop a predictive model based on spectral CT-derived parameters for preoperative assessment of extramural venous invasion (EMVI) in patients with colon cancer. Methods This retrospective study included 235 patients with pathologically confirmed colon cancer...