Chonnam National University Hospital

Life-threatening diffuse alveolar hemorrhage associated with Rhinovirus infection and the potential role of corticosteroids in immunocompetent patients

Rationale: Diffuse alveolar hemorrhage (DAH) is a rare but potentially fatal condition characterized by bleeding into alveolar spaces, most often associated with autoimmune disease or severe infection. Rhinovirus is a common cause of upper respiratory tract infection but is rarel...

Apparent Diffusion Coefficient Composition and Tissue Heterogeneity as Predictors of Functional Outcomes After Endovascular Thrombectomy in Patients With Large Ischemic Core

BACKGROUND: Recent trials established endovascular thrombectomy efficacy in large ischemic cores, yet outcomes remain heterogeneous despite similar infarct volumes, suggesting that current volumetric assessments may not fully capture tissue viability. We examined whether tissue c...

Temporal regulation of activin, follistatin, and growth differentiation factor 15 in the liver and circulation during high-fat diet–induced fatty liver disease

Metabolic dysfunction-associated steatotic liver disease (MASLD) develops over time, yet most hepatokine studies are cross-sectional.We investigated the temporal regulation of the activin-follistatin axis and growth differentiation factor 15 (GDF15) in high-fat diet (HFD)-induced...

Lipid Burden and Efficacy of Preventive PCI of Vulnerable Atherosclerotic Coronary Plaques: Post Hoc Analysis From the PREVENT Trial

BACKGROUND: Preventive percutaneous coronary intervention (PCI) of non–flow-limiting lesions (fractional flow reserve >0.80) that are high-risk plaques has emerged as a potential strategy to reduce cardiac events. However, identifying which lesions derive the greatest benefit fro...

TSH Stimulation Reveals Additional Bone Metastases on [18F]FDG PET/CT in Metastatic Follicular Thyroid Carcinoma

A 62-year-old woman with metastatic follicular thyroid carcinoma underwent 2-deoxy-2-[18F]fluoro-D-glucose ([18F]FDG) PET/CT before a second course of radioactive iodine therapy because of a markedly elevated serum thyroglobulin level (498.0 ng/mL). The initial PET/CT was perform...

A Retrospective Multicenter Study of Measles Seropositivity in Korea from 2014 to 2024

Background: Measles is a highly contagious viral disease requiring high herd immunity.Although the Republic of Korea has maintained measles elimination through national immunization programs, sporadic cases continue to occur.We evaluated age-and period-specific measles immunity l...

Concomitant Anemia and Thrombocytopenia as Clinical Clues to Thrombotic Thrombocytopenic Purpura in Patients with Stroke or Stroke-Like Symptoms

pathic hemolytic anemia (MAHA), fever, thrombocytopenia, renal impairment, and neurological deficits [1].However, this full pentad is observed in only approximately 5 to 10% of patients, whereas thrombocytopenia and MAHA are present in most cases [2, 3].At our tertiary care hospi...

Platform differences in live-streaming commerce: The Role of task-technology fit and social-technology fit in driving consumer engagement and purchase decisions

Live-streaming commerce (LSC) combines online shopping with real-time social interaction, but consumer responses may vary across host platforms. Drawing on Uses and Gratifications as a motivational backdrop and Apparatgeist as a contextual lens, this study treats Task-Technology...

Nationwide Multicenter Laboratory-Based Analysis of Varicella-Zoster Virus IgG and IgM Seropositivity in Korea, 2014–2024

Background: Varicella-zoster virus (VZV) remains an endemic, vaccine-preventable infection in Korea, despite high national vaccination coverage. Understanding long-term population immunity trends is essential for refining the disease-control and immunization policies. In this nat...

Vascular Imaging Features and Time-Specific Recurrence Risk After Craniocervical Artery Dissection

Background and ObjectivesCraniocervical artery dissection (CCAD) is a major cause of stroke in young adults, yet its recurrence risk remains poorly defined because of delayed enrollment in prior research. We aimed to determine the temporal distribution of recurrent ischemic strok...

Robotic bronchial restapling after inadvertent stapling of an endobronchial suction tube: technical note and a prestapling time-out

Abstract Foreign body entrapment during bronchial stapling is rare but may result in severe airway injury. We report an unusual intraoperative complication during robot-assisted thoracic surgery (RATS) lobectomy: inadvertent stapling of an endobronchial suction tube into the righ...

Extended treatment duration and recurrence in successfully treated drug-susceptible pulmonary tuberculosis with cavity on chest radiograph

Background Cavity on chest radiograph is recognized as an independent risk factor for recurrence in pulmonary tuberculosis (TB), but evidence supporting extended treatment in these patients remains limited, particularly in real-world data from Korea. Methods We performed a retros...

Discordant Antitumor Efficacy with Compromised Survival in High-Risk Unresectable Hepatocellular Carcinoma

Background/Objectives: Real-world data in high-risk patients remain limited; this study evaluated survival, safety, and prognostic factors in this patient group. Methods: This multicenter study retrospectively reviewed 783 patients who received Ate/Bev from 2022–2024 across South...

Three-Year Outcomes of Drug-Eluting Stents, Drug-Coated Balloons, and Non-Drug-Eluting Devices in Native Femoropopliteal Artery Disease: An Analysis of the K-VIS ELLA Registry

Background: Although drug-eluting devices have demonstrated improved efficacy in femoropopliteal artery (FPA) disease, evidence on their long-term clinical outcomes in realworld practice remains limited.Methods: Using data from the multicenter Korean Vascular Intervention Society...

Serial Changes in CSF Volume Proportion on Brain CT and 6-Month Neurologic Outcomes After Cardiac Arrest: A 72–96-h Landmark Cohort Study

Background: Single-time-point cerebrospinal fluid (CSF) volume proportion (pCSFV) has shown limited prognostic utility after out-of-hospital cardiac arrest (OHCA). We hypothesized that serial within-patient change in pCSFV (ΔpCSFV), rather than absolute values, would reflect prog...

Autoimmune Gastritis: An Evolving Entity

Autoimmune gastritis (AIG) has long occupied an awkward place in clinical practice.For most of the 21th century, it was viewed mainly through its hematologic endpoint-pernicious anemia-and seen as a rare, late diagnosis of limited relevance to the endoscopist.That perception has...

Cutaneous Langerhans Cell Sarcoma Harboring BRAF V600E Mutation Followed by Chronic Myelomonocytic Leukemia and EBV ‐Positive Diffuse Large B‐Cell Lymphoma

ABSTRACT Langerhans cell sarcoma (LCS) is an extremely rare and aggressive neoplasm of histiocytic and dendritic cell lineage. We report a case of cutaneous LCS in a 74‐year‐old woman, harboring a BRAF V600E mutation and demonstrating an aggressive clinical course, including mult...

Restricted Loss of Life Expectancy in Patients With Acute Myocardial Infarction: A Nationwide KAMIR Registry Study

Background The mortality risk of acute myocardial infarction declines rapidly after the initial period, yet the quantitative measures of residual risk in the follow‐up period remain limited. We aimed to assess restricted loss of life expectancy (LOLE) in patients with acute myoca...

ALKBH10B mediated epitranscriptomic regulation enhances drought tolerance of Arabidopsis thaliana via hormonal cross-talk and sustained photosynthesis

Abstract Key message The m⁶A demethylase ALKBH10B emerges as a crucial post-transcriptional regulator of hormonal crosstalk, photosynthetic maintenance, and mitochondrial energy metabolism to fine-tune plant stress adaptation to drought . Abstract Epitranscriptomic N⁶-methyladeno...

Altered Complement and Tubular Mitochondrial Proteins Are Linked to Graft Loss in DSA+ Antibody–Mediated Rejection

Background: Antibody-mediated rejection (AMR) is the main driver of late kidney allograft loss. Anti-HLA donor-specific antibodies (DSA) are strongly associated with AMR. However, 30-60% of DSA + patients do not develop AMR, raising the possibility of local tissue adaptations to...