Chongqing Dazu District People's Hospital

Successful use of nafamostat mesilate anticoagulation in V-V ECMO for refractory diffuse alveolar hemorrhage secondary to ANCA-associated vasculitis: case report and review of the literature

Diffuse alveolar hemorrhage (DAH) is a life-threatening complication of Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Veno-venous extracorporeal membrane oxygenation (V-V ECMO) serves as a salvage respiratory support for patients with severe hypoxemia u...

DUET‐seq: An Open‐Source Droplet Platform for High‐Fidelity Joint Chromatin and Transcriptome Profiling Reveals Temporal Regulatory Decoupling in Single Cells

ABSTRACT Joint profiling of chromatin accessibility and gene expression in the same cell enables direct linkage of regulatory elements to transcriptional output, but existing approaches remain limited by low co‐capture sensitivity, proprietary platforms, and high costs. Here we p...

The NF-κB pathway in inflammatory responses in preeclampsia

Background: Preeclampsia is a pregnancy-specific hypertensive disorder associated with systemic inflammation, endothelial dysfunction, and adverse maternal and fetal outcomes. The nuclear factor kappa B (NF-κB) signaling pathway has been implicated in inflammatory activation, but...

CT quantification of enlarged inguinal lymph nodes as a diagnostic approach for periprosthetic joint infection after hip arthroplasty

Periprosthetic joint infection (PJI) is a major complication following total hip arthroplasty (THA), posing significant diagnostic challenges. This study prospectively evaluated 114 patients from January 2021 to August 2023, including those with PJI and aseptic loosening, using c...

Temporal dynamics of PrEP adherence, self-efficacy, and risk perception among men who have sex with men in western China: a cross-lagged panel network analysis

<title>Abstract</title> Background Pre-exposure prophylaxis (PrEP) effectively reduces HIV infection risk among men who have sex with men (MSM), but its benefit depends on adherence. The longitudinal item-level relationships among PrEP adherence, self-efficacy, and risk perceptio...

Adherence to the DASH diet moderates the association between sedentary time and the risk of obstructive sleep apnea in a hypertensive rural Chinese population: a cross-sectional study

Obstructive sleep apnea (OSA) and hypertension form a vicious cycle. While sedentary behavior is an emerging risk factor for OSA, and the dietary approaches to stop hypertension (DASH) diet offers cardiometabolic benefits, their interplay in non-obese hypertensive patients remain...