Chinese People's Armed Police General Hospital

FAM45A-Mediated Persistent Memory-Like Fibroblast Reprogramming Drives PM2.5-Exacerbated Allergic Asthma

Abstract Chronic coexposure to fine particulate matter (PM2.5) and house dust mite (HDM) allergen worsens allergic asthma outcomes, yet the stromal cell mechanisms linking combined environmental and allergic risk factors remain incompletely defined. Airway fibroblasts are traditi...