Chinese Center For Disease Control and Prevention

Protocol for the ACTIVE trial: a multicentre, open-label, cluster-randomized controlled trial of a quality improvement programme for older adults with hip fracture in resource-limited hospitals in China

Aims The primary aim of the Action on Hip Fracture Management Quality Improvement (ACTIVE) trial is to evaluate whether a context-tailored quality improvement programme improves health-related quality of life at 120 days after hospital admission, among adults aged 65 years or old...

Plant-based diet and risk of cognitive decline among older adults: a community-based prospective cohort study

Background: Diet serves as a modifiable risk factor for cognitive decline, yet evidence on plant-based diets and cognitive ageing remains limited. We examined the association between plant-based diets and cognitive decline.Methods: A total of 6,721 participants from the Chinese L...

FOXA2 Transcriptionally Activates SIRT1 to Inhibit Cochlear Ferroptosis in Noise-Induced Hearing Loss

Background: Noise-induced hearing loss (NIHL) is a pervasive occupational health challenge, yet the individual susceptibility mechanisms remain unclear. Ferroptosis, an iron-dependent form of programmed cell death, has been implicated in cochlear hair cell damage. This study aims...

From raw to cooked: The impact of cooking on bioaccessibility and health risks of toxic elements in leafy vegetables

Environmental policies in China have significantly reduced toxic element fluxes in soil and air, but slower declines in atmospheric toxic element flux have increased its relative contribution to crop contamination. Leafy vegetables, with their large surface area and high capacity...

Prevalence of Keshan disease at the township level in China: a cross-sectional study

Keshan disease (KD), an endemic myocardiopathy with unclear etiology, lacks primary preventive measures. This study aimed to assess the prevalence of KD at the township level using spatial epidemiology, elucidate its distribution characteristics for further precision classificati...

Temporal trends and age-period-cohort effects of tuberculosis incidence among older adults in western China, 2005–2020

Abstract Background Tuberculosis remains a major public health challenge in China, and older adults in western China bear a disproportionate burden. This study examined the temporal trends in TB incidence among older adults in western China and assessed the independent effects of...

Longitudinal TyG index trajectories and renal function decline in a high cardiovascular-risk Chinese cohort: a sex-stratified analysis

This study aimed to identify longitudinal triglyceride-glucose (TyG) index trajectories and evaluate their association with annual estimated glomerular filtration rate (eGFR) change in a high cardiovascular-risk Chinese cohort, with sex-stratified analyses. A prospective cohort a...