Chinese Academy of Medical Sciences Dermatology Hospital

Lactate suppresses T follicular helper cells in lupus in association with metabolic-epigenetic reprogramming

Aberrant CD4⁺ T cell differentiation, particularly the expansion of T follicular helper (Tfh) cells, is a hallmark of systemic lupus erythematosus (SLE) and is critically dependent on metabolic reprogramming. Although altered lactate metabolism has been implicated in autoimmune d...

Age-related changes of FCGR3A+ natural killer cells and their association with elderly atopic dermatitis

Background The increasing global ageing population has led to a rising prevalence of elderly atopic dermatitis (eAD). Natural killer (NK) cells play an important role in skin homoeostasis; however, their involvement in eAD remains unclear. This study investigates the functional r...

Associations of psoriasis history with general discrimination‐related experiences in US adults

The data underlying this article are publicly available from IPUMS Health Surveys and the National Center for Health Statistics 2023 National Health Interview Survey.

Efficacy evaluation of flap repair after radical excision for axillary hidradenitis suppurativa

The data that support the findings of this study are available from the corresponding author upon reasonable request.

Efficacy and Safety of the First Adalimumab Biosimilar in Chinese Children with Severe Plaque Psoriasis: The PISCES Study, a Multicenter Prospective Study

Adalimumab, a monoclonal antibody targeting tumor necrosis factor-alpha, has been approved for the treatment of severe plaque psoriasis in children aged 4 years and older. Data on its use in the clinical management of pediatric psoriasis in China remains limited. This study is th...