China Rehabilitation Research Center

Sex‐Specific Digital Phenotyping of Lower Urinary Tract Symptoms: A Cross‐Sectional Study of 1586 Adults From 35 Centers in China

ABSTRACT Background and Purpose Lower urinary tract symptoms (LUTS) represent a complex clinical syndrome with significant sexual dimorphism. Traditional “one‐size‐fits‐all” management often overlooks intra‐sex phenotypic heterogeneity. This study utilized unsupervised machine le...

Accelerometer-measured moderate-to-vigorous physical activity patterns and mortality among individuals with venous thromboembolism: a prospective cohort study from the UK Biobank

Although the “weekend warrior” activity pattern has been associated with lower mortality in the general population, whether it is associated with long-term outcomes after venous thromboembolism (VTE) remains unclear. In this prospective analysis, we examined the association betwe...

Therapeutic targeting of TCF/LEF transcription factors in neuropsychiatric disorders via Wnt/β-catenin signaling

The T-cell factor/lymphoid enhancer-binding factor (TCF/LEF) family, comprising TCF1, LEF1, TCF7L1, and TCF7L2, serves as nuclear effectors of the canonical Wnt/β-catenin signaling pathway and plays pivotal roles in neurodevelopment, synaptic plasticity, neuroinflammation, and ce...

Scapular pressure distribution and its association with upper limb function in breast cancer survivors following modified radical mastectomy: a cross-sectional study

Upper limb dysfunction remains a frequent challenge for breast cancer survivors following modified radical mastectomy (MRM) with axillary lymph node dissection (ALND). Although alterations in scapular function may be relevant to postoperative shoulder impairment, scapular-region...

Spinal Magnetic Resonance Diffusion Tensor Imaging (DTI) in OAB and UAB Caused by Tethered Cord Syndrome (TCS): Can the Yield Be Improved?

OBJECTIVE: This study aims to investigate spinal cord abnormalities in patients with Tethered Cord Syndrome (TCS) and lower urinary tract dysfunction using diffusion tensor imaging (DTI). Specifically, it seeks to explore the differences in the extent and severity of spinal cord...

Development of an explainable machine learning model for predicting six-month consciousness recovery in patients with prolonged disorders of consciousness

With advances in emergency care systems, the number of patients with prolonged disorders of consciousness (pDoC) has markedly increased. To optimize the allocation of healthcare resources and mitigate risks, the early and accurate identification of recovery potential in pDoC is e...

Association between post-exercise heart rate recovery and one-year clinical deterioration in COPD: a retrospective longitudinal analysis

The application of cardiopulmonary exercise testing (CPET) for assessing heart rate recovery at 1 min (HRR1) is of significant clinical value in evaluating disease severity, cardiovascular risk, and prognosis in patients with cardiovascular diseases. However, its utility in patie...

Effectiveness of a standardized weaning protocol in tracheostomized patients with prolonged mechanical ventilation: a prospective single-arm interventional trial

Patients requiring prolonged mechanical ventilation (PMV) after tracheostomy represent a severely deconditioned population with high mortality and substantial healthcare burden. Weaning outcomes vary widely across centers, and evidence supporting standardized protocol in dedicate...