China National Pharmaceutical Group Corporation (China)

The role of plasma oxytocin in early-onset schizophrenia: implications for disease severity and early intervention

INTRODUCTION: Early-onset schizophrenia (EOS) is a severe psychiatric disorder with poor long-term outcomes. It offers a unique opportunity to examine the neurobiological mechanisms of schizophrenia without the confounding effects of adult environmental factors. Oxytocin (OXT), a...

Association of neoadjuvant subcutaneous trastuzumab with higher pathological complete response in HER2-positive breast cancer: a real-world doubly robust study

Randomized trials have demonstrated the non-inferiority of subcutaneous (SC) versus intravenous (IV) trastuzumab. Its association with pathological complete response (pCR) in routine neoadjuvant practice warrants further study. The ability of serial ultrasound measurements to dis...

Lithium Ascorbate May Support Weight Loss Within the Depression-Obesity Feedback Loop

Depression and obesity frequently coexist and may reinforce one another through biological, behavioral, and psychosocial mechanisms, complicating both mood management and weight reduction. This paper reviews the depression–obesity feedback loop, current approaches to major depres...