China Animal Disease Control Center

A Method Based on Nanobodies Against AMH to Establish Immunochromatography for Evaluation of Follicular Development in Bactrian Camels

(1) Background: Anti-Müllerian hormone (AMH) is a key indicator for predicting ovarian reserve and fertility. Currently, B-mode ultrasound examination is the primary method for evaluating follicular development in Bactrian camels, although it has several limitations. This study a...

Comparative Immunogenicity of Inactivated H7N9 Avian Influenza Vaccines with Different Internal Gene Backbones

H7N9 avian influenza virus (AIV) poses a persistent threat to poultry and public health. Despite widespread vaccination in China, rapid antigenic drift and reassortment necessitate frequent updates of vaccine strains. Phylogenetic analysis of isolates from Chinese provinces (from...

Self-assembling trivalent nanoparticle vaccine enables multivalent antigen display and potent cross-protection against fowl adenovirus serotypes 4, 8b, and 11

Hepatitis-hydropericardium syndrome, caused by fowl adenovirus serotype 4(FAdV-4), and inclusion body hepatitis, caused by fowl adenovirus 8b and 11 (FAdV-8b and FAdV-11), have become widespread in China, resulting in substantial economic losses. Vaccination remains one of the mo...