Chimie et Interdisciplinarité, Synthèse, Analyse, Modélisation

Breast cancer metabolism and responsiveness to dichloroacetate: relationships with 15N and 13C natural abundance

Abstract Background Metabolic reprogramming is a hallmark of breast cancer (BrCa), with alterations in glycolysis, glutamine metabolism, and the urea cycle contributing to tumour progression. Dichloroacetate (DCA), a pyruvate dehydrogenase kinase (PDK) inhibitor, shifts metabolis...

Enhancing Electrochemiluminescence with Two-ComponentSpontaneously Adsorbed Monolayers and Films

Abstract Multicomponent films offer important opportunities in electrochemiluminescence, ECL, including the possibility to coimmobilize an electron transfer mediator to facilitate the generation of radicals from a coreactant and to enhance indirect ECL at potentials that are lowe...