Children's of Alabama

Early Palliative Care Is Feasible and Acceptable in Pediatric Neuro‐Oncology

BACKGROUND: Children with central nervous system (CNS) tumors face high morbidity and mortality, yet often do not receive palliative care (PC). There is evidence of the benefit of PC in pediatric oncology, though the ideal timing remains unknown. We aimed to evaluate the feasibil...

Comparison of Empiric Antibiotics With and Without MRSA Coverage in Staphylococcal Scalded Skin Syndrome

PURPOSE: Treatment of staphylococcal scalded skin syndrome (SSSS) typically covers methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant S. aureus (MRSA). However, limited data exist to show an optimal antibiotic regimen. We hypothesized that empiric antibi...

Wilms tumor: diagnosis and updates

Although Wilms tumor is the most common malignant renal tumor of childhood, it is an overall rare malignancy with a variety of histological appearances. As clinical trials have sought to further identify groups of patients who can benefit from escalation or de-escalation of thera...

Feasibility of Real‐Time Central Risk Assignment for Children's Oncology Group Pediatric Renal Tumor Trials

BACKGROUND: The Children's Oncology Group (COG) AREN03B2 Renal Tumor Biology and Classification Study undertook real-time central reviews to enable accurate risk stratification for enrollment on therapeutic trials. The present study assessed the feasibility of the central review...