Children’s Hospital of Fudan University Xiamen Branch

A nomogram integrating first-trimester metabolic and angiogenic markers for predicting adverse pregnancy outcomes in gestational diabetes mellitus: development and internal validation

Abstract Background Gestational diabetes mellitus (GDM) is associated with a significantly increased risk of adverse pregnancy outcomes. This study aimed to develop and internally validate a nomogram integrating integrating first-trimester metabolic and angiogenic markers to pred...

Distribution of androgen receptor expression in breast cancer subtypes

This study aimed to analyze the differential expression of the androgen receptor (AR) across molecular subtypes of female breast cancer and to evaluate its significance in breast cancer tissues. Pathological specimens were collected from breast cancer patients who had not undergo...

Development and preliminary evaluation of a WeChat mini-program-based mobile pharmacy management assistance system in a Chinese women and Children’s hospital

Abstract Background Traditional pharmacy management, which relies on paper- and computer-based methods, is often inefficient and inflexible. There is an urgent need to develop support tools to address these challenges. The WeChat mini-program has been applied in multiple fields b...

Fetal brain five-axial planes and 3D-ICRV cerebral surface imaging from 16 to 36 weeks of gestation

Abstract Background Recent advances in fetal neurosonography have increased interest in prenatal cortical assessment. However, the transvaginal approach, while providing superior resolution, is technically complex and limited to specialized settings. Methods This study utilizes a...

Comprehensive genomic characterization of extraintestinal pathogenic Escherichia coli isolated from neonates: multiple center insights into virulence, resistance, and transmission dynamics

Neonatal extraintestinal pathogenic Escherichia coli (ExPEC), which can cause severe long-term sequelae by systemic infections, is gradually becoming the primary pathogen threatening neonatal health. The lack of large-scale genomic epidemiological investigation hinders further un...

Multi-level static and dynamic graph-theoretical analyses of resting-state functional networks in a Chinese cohort of preterm neonates

Preterm birth influences early functional brain maturation at term-equivalent age. Using resting-state functional magnetic resonance imaging from a large Chinese neonatal cohort (62 term-born and 107 preterm neonates), we examined static and dynamic network organization using mul...