Children's Hospital & Medical Center

Probing Executive Function in the Toddler Data Desert: A Touchscreen fNIRS Study of Working Memory and ADHD-Related Symptoms

Attention-deficit/hyperactivity disorder (ADHD) is associated with early differences in attentional control and working memory (WM), yet relatively few paradigms are developmentally feasible across the toddler-to-preschool period while also distinguishing spatial from featural in...

Pharmacokinetics and Toxicity Assessment of Artesunate and Its Metabolite, Dihydroartemisinin, in NOD Scid Gamma Mice

Artesunate (ART) is an FDA-approved antimalarial drug and is currently being repurposed for various solid tumor treatments. However, there are no safety or pharmacokinetic (PK) studies in mice exploring its potential application in murine brain tumor models. This study aims to de...

Validation of AACN’s Healthy Work Environment Assessment Tool–Team

Background In 2024, the American Association of Critical-Care Nurses (AACN) updated the Healthy Work Environment Assessment Tool (HWEAT), renamed HWEAT-Team. Objective Validating HWEAT-Team for interprofessional use. Methods This was a multisite, descriptive, nonexperimental corr...