Children's Hospital Colorado

Tibial Bone Shape Is Sport Dependent and More Symmetrical in High-Impact Athletes: A Cross-Sectional Study

Introduction: Multidirectional sports introduce unique forces to the tibia that potentially induce more symmetrical distribution of bone mass and lower bone stress injury risk, when compared to unidirectional sports. Purpose: To compare tibial shaft size, shape, and estimated str...

High-Value Care in Pediatric Critical Care: Intravenous to Enteral Gastrointestinal Medications

Advancing pediatric critical care medicine includes identifying and reducing health care costs while maintaining—and even enhancing—the delivery of high-value care. Gastrointestinal (GI) prophylaxis (PPX) is commonly prescribed for children in the pediatric intensive care unit (P...

What’s Old Is New Again: Varicella

The availability of a varicella vaccine has led to significant decreases in incidence of this once-common childhood disease. In the setting of rising vaccine hesitancy, health care clinicians are now more frequently facing questions about infections caused by varicella zoster vir...

Safety and Tolerability of Chronic Carvedilol in Pediatric Dilated Cardiomyopathy: A Report from the Pediatric Cardiomyopathy Registry

Long-term studies on safety of beta-blockers in pediatric heart failure (HF) are scant. We describe the safety profile, dose ranges, and tolerability of carvedilol in pediatric dilated cardiomyopathy (DCM). The Pediatric Cardiomyopathy Registry (PCMR) was used to identify patient...

Percentiles for crying, regurgitation, stool consistency, and CoMiSSTM in presumed healthy infants

Parents frequently consult health care professionals because of infant regurgitation, crying and stool consistency. The Cow’s Milk-related Symptom Score (CoMiSS TM ) is an awareness tool for cow’s milk allergy. We aimed to characterize the distribution of CoMiSS items in presumed...

Effect of time to palliative epilepsy surgery on outcomes

Abstract Objective Epilepsy duration is a modifiable risk factor in the outcome of definitive epilepsy surgery; however, an analogous effect in palliative procedures has not been shown. We reviewed the Pediatric Epilepsy Surgery Database data for an association between epilepsy d...