Children's Hospital 1

Fulminant multisystem adenovirus-associated illness with cerebrospinal fluid PCR positivity and minimal pleocytosis in previously healthy toddlers: a case series

Central nervous system manifestations of human adenovirus infection are uncommon in immunocompetent children and may be difficult to recognize when routine cerebrospinal fluid (CSF) indices are normal or only minimally abnormal. We report a severe pediatric case series characteri...

Complete androgen insensitivity syndrome in two siblings with a pathogenic androgen receptor gene variant: a case series

Complete androgen insensitivity syndrome (CAIS) is a rare X-linked disorder caused by pathogenic variants in the androgen receptor (AR) gene, resulting in complete resistance to androgen action in individuals with a 46,XY karyotype. Familial cases of CAIS provide important insigh...

Characterization of gut microbiota in Vietnamese children under 5 years of age with acute and persistent diarrhea

Gut microbiota alterations have been increasingly associated with diarrheal diseases, a leading cause of morbidity and mortality in children under 5 years of age. However, explorations examining microbiota profiles across different diarrhea durations remain limited. Our study inv...

Genetics in Heterotaxy: A Case Series and Literature Review on DNAH9 , PKD1L1 , MMP21 , and GDF1

Heterotaxy (HTX) is a rare condition characterized by complex congenital heart defects and a wide spectrum of extracardiac abnormalities that significantly impact survival. While molecular diagnosis is essential for clinical management, next-generation sequencing (NGS) currently...

Caregiver perspectives on inpatient service quality at a pediatric hospital in Vietnam: a mixed-method study

Assessing the quality of inpatient services is essential for improving healthcare performance and ensuring patient-centered care, particularly in pediatric hospital settings. Although Vietnam has implemented national hospital quality assurance frameworks, empirical evidence on pe...

Neonatal antibody levels and treatment outcomes following maternal vaccination among NICU infants exposed to COVID-19 during pregnancy

The COVID-19 pandemic has profoundly affected maternal and child health worldwide, with pregnant women being particularly vulnerable to complications. Vaccination during pregnancy has been shown to generate protective antibodies offering passive immunity to neonates, though conce...