Institution
Chiba University Hospital
Recent research
- Engineering & TechnologyOpen access
Background/Objectives: Monitoring and evaluating respiratory rate (RR) plays a critical role during emergency transport. Conventional RR measurement methods have primarily relied on electrocardiogram-based approaches, which are susceptible to large errors caused by patient body m...
- Health & MedicineOpen access
Abstract Background Third-party accreditation and the visibility of educational outcomes may influence medical students’ choice of training sites; however, national evidence of their effect in Japan is limited. This study examined whether hospital characteristics—especially Japan...
- BiologyOpen access
Neural Correlates of Apathy in Multiple System Atrophy: A Clinical and Perfusion Imaging Study
BACKGROUND: Apathy is a frequent nonmotor symptom of multiple system atrophy (MSA) that worsens quality of life. Although frontostriatal dysfunction has been implicated in apathy, its neural basis in MSA remains insufficiently characterized. OBJECTIVES: To identify the neural sub...
- Health & MedicineOpen access
Post-induction hypotension is a common complication of general anesthesia and has been associated with adverse postoperative outcomes. We examined factors associated with post-induction minimum mean arterial pressure (MAP) and explored risk-profile–based model-derived norepinephr...
- BiologyOpen access
Abstract Background Threshold tracking transcranial magnetic stimulation (TT-TMS) is increasingly recognized as a promising diagnostic tool for estimating motor cortical excitability, and previous studies have shown hyperexcitability in patients with amyotrophic lateral sclerosis...
- Health & MedicineOpen access
Background Pulmonary hypertension (PH) complicates interstitial lung disease (ILD) and worsens patient outcomes; however, data beyond idiopathic pulmonary fibrosis (IPF) are limited. This study evaluated PH prevalence in progressive pulmonary fibrosis (PPF) and identified predict...
- Health & Medicine
Electroconvulsive therapy (ECT) is a well-established treatment for severe or treatment-resistant major depressive disorder and schizophrenia, often leading to rapid symptom improvement. However, ECT can rarely cause adverse psychological effects, including new-onset auditory hal...
- Health & MedicineOpen access
Electric appliance usage measured by a sensor and frailty in Japan
Abstract Background The measurement of in-home activity for frailty is limited by poor adherence, recall bias in self-reported measurements, and difficulties with long-term tracking. Data on electrical appliance usage can estimate in-home activities and be measured every minute,...
- Biology
Abstract Doxorubicin (DOX)-loaded liposomes are one of the most established and clinically relevant nanomedicines in a drug delivery system. In this study, we elucidate the mechanistic relationships among cooling rate, lipid composition, and the resulting morphological evolution...
- BiologyOpen access
Abstract Topic Esophageal Cancer: Molecular Biology/Pathology Background Esophageal squamous cell carcinoma (ESCC) shows limited response to anti-PD-1 monotherapy, prompting interest in combination treatments. Pin1, highly expressed in ESCC and other cancers, drives malignancy. S...