Chettinad Academy of Research and Education

Assessment of Nicotine Dependence and its Determinants Among Tobacco Users in Rural Community of Tamil Nadu

Abstract Introduction: As a major cause of disease and mortality, tobacco smoking continues to be a major global public health concern. However, there is a limited understanding of the specific determinants of nicotine dependence in rural settings like Tamil Nadu. The purpose of...

Midlife window: moderate caffeine consumption and reduced dementia risk

Moderate caffeine consumption during midlife is associated with neuroprotective potential, particularly in reducing the risk of dementia. This targeted perspective synthesizes epidemiological and mechanistic evidence on moderate caffeine consumption during midlife (ages 40–65 yea...

Explainable AI-assisted sustainable performance optimization of Nano-enhanced rapeseed oil blends in ci engines for optimized engine operation

This study investigates the influence of advanced fuel injection timing on the performance, combustion, and emission characteristics of a compression ignition engine fueled with a rapeseed oil emulsion–pentanol blend (70D25GS5P) supplemented with 150 ppm TiO₂ nanoparticles. Exper...

Teprotumumab in thyroid eye disease: Evidence, challenges, and the Indian perspective

ABSTRACT Thyroid eye disease (TED) represents a significant clinical burden in patients with Graves’ disease, with limited treatment options beyond glucocorticoids and conventional immunosuppression. Teprotumumab, a human monoclonal antibody targeting the insulin-like growth fact...

Photocatalytic nanomaterials: present and future

Abstract Photocatalysis is a sustainable and light-driven technology increasingly recognized for its potential to address pressing environmental and energy challenges. Incorporating nanomaterials has notably enhanced photocatalytic performance by offering high surface area, tunab...