Chelsea and Westminster Hospital NHS Foundation Trust

Growth trajectory and miscarriage diagnosis threshold in early IVF pregnancy: multicenter study

ABSTRACT Objectives To characterize early‐pregnancy ultrasound findings in pregnancies conceived via in‐vitro fertilization (IVF) for which gestational age is known precisely based on the date of embryo transfer (ET), and to examine their association with first‐trimester pregnanc...

Impact and sustainability of master trainer-led obstetric emergency skills training in Uganda: a qualitative study

BACKGROUND: Maternal mortality remains a major challenge in Uganda, where the maternal mortality ratio is 189 per 100,000 births - fifty time higher than in the UK. The Royal College of Obstetricians and Gynaecologists' Excellence in Obstetric Skills (EOS) and Resilience in Obste...

Data distribution impacts the performance and generalisability of contrastive learning-based foundation models of electrocardiograms

Contrastive learning is a widely adopted self-supervised pretraining strategy, yet its dependence on cohort composition remains underexplored. We present Contrasting by Augmented Patient Electrocardiograms (CAPE) foundation model and pretrain on four cohorts (n = 5,203,269), from...

Implementing telemedicine under polycrisis: a mixed-methods case study from Myanmar using the RE-AIM framework

Myanmar’s March 2025 7.7-magnitude earthquake intersected with conflict, governance breakdown, and economic collapse, leaving 12.9 million people needing health assistance, yet evidence on how telemedicine functions under such polycrisis conditions remains limited. We conducted a...

Anticoagulation and Antiplatelet Therapy in Chronic Subdural Hematoma: A Multicenter Evaluation

BACKGROUND AND OBJECTIVES: Chronic subdural hematomas (cSDH) are among the most common neurosurgical pathologies. Older adults also often have comorbidities treated with anticoagulant and antiplatelet (ACAP) medications. Managing clinicians frequently must weigh the benefits and...

Does Waiver of Informed Consent in Low-Risk Randomised Controlled Trials Improve Research Inclusion? Insights from a Review of the UK Health Research Authority Confidentiality Advisory Group Register

Low-risk pragmatic trials improve clinical services. Informed consent is gold standard to ensure ethical research. However, its implementation can impact participation of underserved groups who face disproportionate barriers around communication, health and research literacy, and...