Charing Cross Hospital

Decoding the causes of ischemic stroke despite ongoing oral anticoagulation and their clinical impact: the ASPERA-R study

BACKGROUND: Oral anticoagulants (OACs), including vitamin K antagonists and direct OACs, reduce stroke risk in atrial fibrillation (AF), yet breakthrough ischemic stroke still occurs in 1-2% of patients annually despite adequate therapy. The mechanisms underlying these events rem...

Cocaine‐Induced Midline Destructive Lesions: A Historical Review of Diagnostic Mimicry

ABSTRACT Objective To review the historical evolution of cocaine‐induced midline destructive lesions (CIMDL), from cocaine's medical introduction to contemporary diagnostic classification. Data Sources PubMed/MEDLINE, Embase, Scopus and Google Scholar were searched from inception...

The mirrored burden and accountable handovers in cancer survivorship: co‑designing a post‑treatment transition standard

Post-treatment transitions after active cancer care often lack clear ownership, timelines and closure rules, shifting coordination work onto survivors and staff. We aimed to identify how these failures arise and to co-design a handover standard for post-treatment survivorship car...