Changsha University

Eggshell-Templated Mn-Doped Hydroxyapatite Composite Scaffold: Coupling ROS Scavenging with Piezo1 Activation for Bone Regeneration

Abstract The treatment of critical-sized bone defects remains challenging due to immune microenvironment dysregulation characterized by excessive ROS, persistent inflammation, and apoptosis, which impede tissue regeneration. Conventional biomaterials often overlook the unique str...

Seismic control of two adjacent structures connected by an energy dissipation enhanced torsional eddy current damper: Optimum design and performance analysis

As urban space becomes increasingly constrained, structural spacing is often minimized within code-permitted limits, making closely spaced adjacent structures increasingly common. Under earthquakes, however, large relative motions between adjacent structures can increase the pote...

Dynamic characteristics of tower response of a FOWT under wind-wave misalignments and mooring line failures

Floating offshore wind turbines (FOWTs) enable energy harvesting from shallow and deep-water regions with high wind potential. However, the structural performance of their towers is sensitive to wind–wave misalignment and mooring line failure. This study investigates the tower re...

Nuclear and Renewable Energy Transitions for Global Sustainability: Exploring the Interactions of Tourism Development and Economic Drivers

ABSTRACT In light of exacerbating climate change issues, recent environmental policy reforms have attempted to balance economic growth and environmental conservation to foster a sustainable development transition. To further debate the scope of decarbonization policies, this stud...

Annealing‐Induced Crystalline Reconstruction and Toughening Mechanisms in β‐Nucleated Long Glass Fiber‐Reinforced Polypropylene Random Copolymer

ABSTRACT Long glass fiber‐reinforced modified polypropylene random copolymer (LPM) systems are widely applied in lightweight structural components. However, rapid injection molding induces heterogeneous crystallization, limiting mechanical performance. Moreover, the intrinsic bri...

Low-Shrinkage 3D-Printed Polymeric Microneedle Arrays with Electroless Silver Coating for Enhanced Thermal and Mechanical Performance in Dermatological Applications

Microneedling has found various applications in dermatology recently. However, many problems still need to be solved in the fabrication of high-aspect-ratio polymeric microneedles with good mechanical strength, dimensional accuracy and thermal conductivity for energy-assisted tre...

Outward Charge-Enriched Boundaries Stabilize Halide–Sulfide Solid–Electrolyte Interfaces

Abstract Halide–sulfide bilayer electrolytes offer a practical route toward all-solid-state lithium batteries by combining the high-voltage compatibility of halide electrolytes with the favorable interfacial contact and Li+-transport characteristics of sulfide interlayers. Howeve...

Ultra-sensitive 2D Dion−Jacobson perovskite phototransistors for optoelectronic neuromorphic computing

Metal halide perovskite semiconductors demonstrate significant advantages over traditional semiconductor materials in next-generation weak-light-responsive devices, owing to their exceptional photoelectric conversion capabilities and outstanding charge transport properties. Under...

Impact of Climate Change on Sustainable Development in China: A Regional Metabolism Perspective

ABSTRACT Climate change poses considerable challenges to global communities. This study proposes a novel framework that integrates seasonality and resilience to analyze regional metabolic responses to climate change in China. By using urban metabolism based on emergy analysis, th...

Exosome-packaged ILK from healthy female serum stimulate osteogenesis via the MAPK signaling pathway

The pathogenesis of osteoporosis (OP) is multifactorial, with impaired osteogenic differentiation of bone marrow stromal cells (BMSCs) serving as a fundamental pathological basis. Enhancing osteogenesis is a key strategy for OP therapy. Exosomes are recognized as promising cell-f...

Feedback Configurations in Interpreting Teaching: Understanding Teachers’ Feedback Belief‐Practice Tensions

ABSTRACT Teachers’ beliefs are noted not to always align with their practices, and such mismatches may in fact reflect teachers’ situated responses to contextual demands. Existing studies have largely focused on corrective feedback in second language teaching and typically examin...

A Gapless T2T Genome and Population-Scale Resequencing of Adzuki Bean Reveal Centromere Evolution and Accelerate Molecular Breeding

Abstract The adzuki bean (Vigna angularis) is an economically and nutritionally significant legume species. Using a multi-strategy sequencing approach, a gapless, telomere-to-telomere (T2T) genome assembly of an elite cultivar, Jihong 16 (JH16), was generated. The genome size was...

Multifunctional Diluent Enables High‐Voltage and Flame‐Retardant Potassium‐Ion Batteries

ABSTRACT Potassium‐ion batteries (PIBs) emerge as a highly promising candidate system in large‐scale energy storage, owing to their abundant resources, low cost, and potentially high operating voltage. However, the current development of PIBs still faces core bottlenecks such as...

Nickase-based suppression of self-ligation in long sticky-end adapters for next-generation sequencing library preparation

The correctness and efficiency of the adapter connection are important factors affecting the quality and yield of the libraries in next-generation sequencing (NGS). Lengthening the sticky ends of the adapters and the targets can effectively improve the efficiency of ligation, how...

Establishing a Semen Cryobank for Yan Goose: Optimized Collection and Cryopreservation

Yan goose, a representative Chinese local breed, requires genetic resource conservation. To address this, we optimized a semen cryopreservation protocol for Yan geese and validated its feasibility in large-scale cryobank production. Using motility of frozen-thawed sperm (MFS) as...

YOLOv11-SR: An Enhanced YOLOv11-Based Framework for Defect Detection in Complex Substation Inspection Images

Accurate detection of explicit faults in substation equipment is critical for intelligent substation inspection. However, practical inspection scenes often involve small objects, blurred boundaries, background clutter, occlusion, and large-scale variations, which significantly ch...

Peukert‐Informed Prediction and Screening of Manganese‐Based High‐Rate Potassium Cathode

ABSTRACT Manganese‐based layered oxides have emerged as promising cathode materials for potassium‐ion batteries owing to their low cost, environmental benignity, structural diversity, and high theoretical capacity, yet suffer from poor rate performance. Compositional regulation o...

A Parallel‐Computing Based Topology Optimization Method of Bi‐Modulus Material Structures With Large Property Difference

ABSTRACT Engineering materials frequently exhibit considerable disparities between their tensile and compressive moduli. However, there are some difficulties in existing topology optimization methods for material structures with large disparities between their tensile and compres...