Chang Gung Children's Hospital

Continuous infusion of granulocyte colony-stimulating factor is associated with an advantage in neutrophil recovery in pediatric oncologic disorders

INTRODUCTION: The use of intensified chemotherapy has significantly improved overall survival (OS) and relapse-free survival (RFS) in cancer patients. However, it also increases the risk of chemotherapy-induced neutropenia (CIN). Granulocyte colony-stimulating factor (G-CSF) is c...

Anakinra in Severe RSV-Associated Autoinflammatory Encephalopathy With Delayed ADEM-Like Changes

Respiratory syncytial virus (RSV)-associated encephalopathy is an uncommon but potentially devastating complication in children. Increasing evidence suggests that infection-triggered neuroinflammation rather than direct viral invasion underlies neurologic injury in a subset of pa...

Disproportionate Subgaleal Hemorrhage in an Infant: Abuse or Bleeding Disorder?

Subgaleal hemorrhage is uncommon in infants beyond the newborn period and, when disproportionate to the reported causal trauma, raises suspicion for child abuse. We describe a 9-month-old girl who developed a large right subgaleal and small epidural hematoma after a 50 cm fall. I...