Chang Bing Show Chwan Memorial Hospital

Single-Lens Reconstructed Three-Dimensional Versus Two-Dimensional Visualization in Uniportal Full-Endoscopic Unilateral Laminotomy with Bilateral Decompression for Lumbar Spinal Stenosis: A Retrospective Comparative Study

Background: Full-endoscopic unilateral laminotomy with bilateral decompression (ULBD) through a single portal lacks stereopsis, which dual-lens three-dimensional (3D) endoscopes cannot supply. This study evaluated whether a single-lens 3D reconstructed system shortens key operati...

Species-Dependent Citrus–Simvastatin Interaction Profiles in an Acute Rat Model: Integrating Drug Disposition, Hepatic Redox, and Complementary Computational Analysis

Abstract Citrus species differ widely in flavonoid chemistry, yet grapefruit has come to represent the genus in citrus–statin interactions. To test whether this translates into species-dependent interaction profiles, six flavonoid-profiled citrus peel extracts (Citrus limon, C. d...

Reproducibility-driven clinical translation of spatial multi-omics in precision medicine

Spatial multi-omics has emerged as a transformative approach for decoding tissue architecture by simultaneously profiling transcriptomic, proteomic, and epigenomic layers within their histological context. Yet despite rapid technological diversification, the transition from explo...

Biomechanical comparison of mini-plate and screw fixation in minimally invasive distal metatarsal osteotomy for hallux valgus

Aims To biomechanically compare the stability of mini-plate and dual-screw fixation following minimally invasive distal metatarsal osteotomy for hallux valgus, with an emphasis on early-stage stability under clinically relevant loading conditions. Methods Three fixation configura...

The double-decking method for rezūm water vapor therapy in benign prostatic hyperplasia: volumetric, functional, and dosimetric outcomes

Abstract Background Lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) significantly impact quality of life in aging men. Conventional Rezūm water vapor therapy consistently achieves only a modest 25–30% prostate volume reduction, leaving a clinic...

Algorithmic Prognostication in Female Oncofertility Counseling: Ethical Challenges of Bias, Autonomy, and Predictive Uncertainty

Advances in machine learning, predictive analytics, and clinical prediction modeling have accelerated the development of algorithmic tools for estimating reproductive outcomes after cancer treatment. In female oncofertility counseling, these models may support individualized asse...

Simulation-based ultrasound-guided lumbar puncture training using a flipped classroom: a single-arm pilot programme evaluation

Abstract Background Traditional landmark-guided lumbar puncture (LP) has high failure rates among novice emergency medicine (EM) clinicians. While ultrasound guidance improves success, structured training models remain limited and expensive. We evaluated a cost-effective, simulat...