CHA University

Claims-defined hepatic steatosis compatible with MASLD and reproductive outcomes after the first observed embryo transfer: a Korean nationwide cohort study

Metabolic dysfunction–associated steatotic liver disease (MASLD) is increasingly prevalent among women of reproductive age; however, its association with reproductive outcomes after in vitro fertilization (IVF) remains insufficiently characterized in population-level data. We eva...

Hyaluronic Acid Hydrogel Incorporating Dexpanthenol-Engineered Extracellular Vesicles for Accelerated Wound Closure and Mitigated Secondary Infection Risk

Background: Loss of epithelial integrity leaves the wound bed open to opportunistic bacterial colonization, and the risk of secondary infection persists for as long as the defect remains unclosed. Wound dressings must therefore provide an immediate external barrier while accelera...

Prenatal PM2.5 exposure drives epigenetic reprogramming of fetal macrophages linked to atopic dermatitis

Abstract Prenatal environmental exposures are increasingly recognized as contributors to atopic dermatitis (AD), yet the underlying mechanisms remain unclear. Fine particulate matter (PM 2.5 ), a complex mixture of airborne pollutants, has been associated with elevated risk of al...

Harnessing Gradient Topography and Dual‐Mode Bioactive Delivery via Bone‐Adhesive Exosome Mimetics for Rotator Cuff Tendon–Bone Interface Repair

ABSTRACT Rotator cuff repair frequently fails because the native enthesis relies on a continuous structural and compositional transition from tendon to bone. Here, we present an enthesis‐mimetic, dual‐gradient scaffold that couples a continuous random‐to‐aligned fiber orientation...