Centro Universitário de Araraquara

Histatin-Based Metallopeptides Target Secondary Biofilms Derived from Candida albicans Persister Cells in Recurrent Vulvovaginal Candidiasis

Biofilm-associated persister cells contribute to the recurrence and treatment failure of Candida albicans infections. Here, two Histatin 5-derived peptides (P1 and P2) and their silver(I)-coordinated derivatives (M1 and M2) were evaluated against a vaginal C. albicans clinical is...

Comparative efficacy of platelet-rich fibrin protocols for alveolar ridge preservation: a systematic review and network meta-analysis

Abstract Objectives This systematic review and network meta-analysis (NMA) aimed to evaluate the effects of platelet-rich fibrin (PRF) in alveolar ridge preservation (ARP), as well as to compare and rank different PRF protocols according to their relative effectiveness. Methods E...

Zerumbone combined with antimicrobial photodynamic inactivation reduces growth of Candida albicans biofilms and modulates virulence gene expression

Abstract Candida albicans biofilms represent a clinical challenge due to their protective extracellular matrix and the resistance to conventional antifungals. This study investigates the strategy of combining the phytochemical zerumbone (ZER) with antimicrobial photodynamic inact...

Phylogroups, virulence factors, and antimicrobial susceptibility of uropathogenic Escherichia coli isolates from dogs at a veterinary hospital in southern Brazil

Escherichia coli , besides being an important commensal of the intestinal microbiota, can cause infections in different sites in humans and domestic animals. There has been an increasing frequency of multidrug-resistant strains, and in light of this, the present study aimed to ch...

Self-medication and psychological symptoms among undergraduate health science students: exploratory associations with religiousness and spirituality in a cross-sectional study

Undergraduate health science students experience academic, clinical, and social demands that may affect psychological well-being and influence self-care practices, including self-medication. Religiousness and spirituality may be associated with how students experience and interpr...

Fast adsorption of Mn2+ and Zn2+ on commercial LTA zeolite: kinetics, equilibrium, and preliminary reuse assessment

Abstract Commercial LTA-type zeolite was evaluated for the adsorption of Mn 2+ and Zn 2+ from aqueous solutions, with emphasis on the relationship between framework properties and adsorption behavior. Despite its very low BET surface area, the zeolite showed rapid and highly effi...

Simultaneous Paranasal Augmentation and Le Fort I Osteotomy Using a Patient-Specific Implant Designed to Share the Fixation Space: Two-Year Clinical Outcomes

BACKGROUND: Residual paranasal concavity may persist after Le Fort I osteotomy despite adequate maxillary repositioning, limiting the aesthetic impact of orthognathic surgery. Simultaneous paranasal implant placement is rarely reported due to spatial conflict with rigid internal...

Smart Coatings Integrating Antimicrobial and Tissue‐Remodeling Functions for Implant Interfaces

AIM: This study aimed to assess the antimicrobial performance and biocompatibility of our drug delivery platform, based on layer-by-layer (LbL) coating incorporating tetracycline (TC) complexed with anionic β-cyclodextrin (TCβCD) and a pH-responsive poly(methacrylic acid) (PMAA)...

Pharmacological Modulation of Nrf2 Signaling Regulates Oxidative Stress, Inflammation, and Alveolar Bone Loss in Experimental Periodontitis

AIM: To investigate whether pharmacological modulation of Nrf2 signaling influences oxidative stress, inflammatory responses, and periodontal tissue destruction in experimental ligature-induced periodontitis. METHODS: Ligature-induced experimental periodontitis was established in...

Season-long match external loads in starters vs. non-starters in Brazilian professional women’s soccer

This study aimed to compare match external loads between starters and non-starters in Brazilian professional women’s soccer. Methods: In this prospective cohort, seventy outfield players (60.93 ± 6.10 kg; 166.39 ± 6.17 cm) from three teams competing in Brazil’s top division (Séri...