Centro Andaluz de Biología Molecular y Medicina Regenerativa

Mules in the Antiquity of Southern Iberia revealed from proteomics

The management of equids in the Iberian Peninsula during the Iron Age (first millennium BCE) provides a key archaeological context for investigating the emerging stages of confluent breeding of horses ( Equus caballus ) and donkeys ( Equus asinus ). This scenario provided the ear...

DNA end-resection is stimulated by an interaction between BRCA1 exon 11 and TOPBP1

Abstract Approximately 60% of the tumour suppressor protein BRCA1 is encoded by a single exon. Many tumours carry mutations in this exon, often resulting in exon skipping and thus a protein of a severely reduced size. Although none of the well-described protein domains of BRCA1 a...