Centre of Advanced Studies

Assessing the impacts of sufficient and reliable electricity in low-resource healthcare facilities

Health systems across sub-Saharan Africa often lack the electricity needed for lighting, medical, diagnostic, and sterilization equipment, and refrigeration. More than one billion people globally rely on facilities with no electricity or a highly unreliable supply. Using survey d...

Integrating molecular engineering and artificial intelligence to overcome clinical and manufacturing challenges in CAR-T therapy

Chimeric antigen receptor (CAR) T-cell therapy has demonstrated remarkable efficacy in addressing hematological malignancies. However, its broader clinical application in other cancer types is still limited by key challenges like antigen escape, on-target/off-tumor toxicity, redu...

A network-driven antiviral discovery pipeline for emerging RNA viruses: a critical perspective from the Red Mexicana de Desarrollo de Antivirales (RMDA)

INTRODUCTION: RNA viruses impose a disproportionate burden of emerging and reemerging infectious diseases in Latin America, yet antiviral discovery in the region remains fragmented, target-limited, and frequently disconnected from translational pathways. This perspective discusse...

Can a nonstandard invisible pair mimic the Michel distribution?

We ask whether a measured Michel distribution, apparently in excellent agreement with the Standard Model interpretation of the \ell_i \to \ell_j \nu\bar\nu <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"> <mml:mrow> <mml:msub> <mml:mi>ℓ</mml:mi> <mml:mi>...