Centre international de recherche sur le cancer

Prospective analysis of pre-diagnostic untargeted plasma metabolomics and risk of triple-negative breast cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)

Triple-negative breast cancer (TNBC) accounts for 10–15% of newly diagnosed breast cancer, and its aetiology is poorly understood compared to other breast cancer subtypes. We applied untargeted metabolomics to identify novel biological pathways associated with TNBC risk and poten...

Early evaluation of the WCT EVI MAP project: implementation, challenges, and emerging impact on evidence-based tumour classification

<ns5:p>Background The WHO Classification of Tumours (WCT) underpins cancer diagnosis globally, but the evidence-base used to inform tumour classification has never been systematically appraised. The WCT EVI MAP project was designed to address this need by developing a structured,...