Centre Hospitalier Universitaire de Limoges

Technical Refinements in Brain-dead Donor Uterus Transplantation: Lessons From the 3 First Cases in France.

Background: Uterus procurement from brain-dead donors during multiorgan procurement for uterus transplantation (UTx) presents a technical challenge because the uterus is not a vital organ and also because of the need to harvest uterine and ovarian veins for transplantation. The a...

Handwriting Isochrony in Autistic and Non-Autistic Children

Handwriting difficulties are frequently reported in autistic children and may interfere with academic performance. However, whether fundamental motor principles such as isochrony are preserved in autism remains largely unexplored. To address this question, fifty-five autistic and...

Global Incidence of All-Cause Dementia

Importance Global dementia incidence estimates are limited by underrepresentation of low- and middle-income countries and heterogeneous analytic methods. Due to these limitations, true understanding of the global dementia landscape remains incomplete. Objective To identify dement...

Subcutaneous isatuximab by on-body-injector plus bortezomib, lenalidomide, and dexamethasone in newly diagnosed transplant-ineligible multiple myeloma: ISASOCUT study

Isatuximab–bortezomib–lenalidomide–dexamethasone (Isa-VRd) has emerged as a standard of care for newly diagnosed multiple myeloma transplant-ineligible patients. A subcutaneous (SC) formulation of isatuximab delivered via an on-body injector (OBI) has been developed to facilitate...

Serum GFAP and Age Accurately Distinguish AQP4 ‐ IgG Positive and Double Seronegative NMOSD From MOGAD After a Recent Attack

BACKGROUND: Serum neurofilament-light chain (sNfL) and glial fibrillary acidic protein (sGFAP) are associated with multiple sclerosis (MS) activity. This study aimed to identify patient- and disease-level determinants of sNfL and sGFAP and to evaluate their ability to support dif...

Occurrence and Genomic Characterization of Listeria monocytogenes ST121 in Animal-Derived Food Samples from Bejaïa, Algeria

Listeria monocytogenesis an important foodborne pathogen that can cause severe invasive disease in vulnerable populations. This study assessed the occurrence of L. monocytogenes in animal-derived foods collected in Bejaïa, Algeria, and characterized recovered isolates using whole...

Association Between Therapeutic Education Delivered by a Community Post-Stroke Rehabilitation Team and Improvement in the Frenchay Activities Index: A Retrospective Cohort Study

Background Social participation is frequently impaired after stroke. Therapeutic patient education (TPE) may promote self-management and community reintegration, but evidence regarding home-based programs delivered by Community Stroke Rehabilitation Teams (CSRTs) remains limited....

Towards a deep-learning genomic tool for risk stratification and diagnostic support in sporadic ALS

Abstract Background A variety of common and rare genetic factors have been implicated in the development of amyotrophic lateral sclerosis (ALS), and the evidence is that a genetic component is present in most affected individuals. However, our current understanding of ALS genetic...