Centre Hospitalier Universitaire de La Réunion

Beyond counting errors: clinical pathway-specific preanalytical risk profiles in surgical pathology

To determine whether clinical referral pathways exhibit distinct preanalytical risk profiles that could complement conventional laboratory-wide quality assessment in surgical pathology. We conducted a retrospective observational study of prospectively recorded preanalytical non-c...

Cross-protection of wildtype and vaccine-derived chikungunya virus antibodies against chikungunya and Mayaro viruses in mice

Abstract The live-attenuated vaccine IXCHIQ against chikungunya virus (CHIKV) was approved in 2023, with its efficacy evaluated using human neutralizing antibody titers as surrogate effectiveness criterion. Previous in vivo studies assessed its efficacy at high CHIKV-specific ant...

Functional orthopedic outcomes in children with myelomeningocele across the Indian Ocean region: a cohort study

In patients with a myelomeningocele, ambulation and autonomy play a significant role in determining their quality of life and participation. The objective of this study was to describe functional orthopedic outcomes of children with myelomeningocele cared for or referred to a uni...

What a highly monitored chikungunya epidemic reveals about preparedness for Europe and beyond

The 2024–25 chikungunya epidemic in Reunion Island illustrates the challenge of translating early warning into timely public-health action during fast-moving arboviral outbreaks. Despite advanced surveillance, the epidemic accelerated rapidly and placed substantial pressure on pr...

Complement C3a receptor expression is associated with distinct immune microenvironmental profiles in clear cell renal cell carcinoma

The complement receptor C3aR has emerged as an important regulator of tumor–immune interactions in several solid cancers. However, its cellular distribution and relationship with the immune microenvironment in clear cell renal cell carcinoma (ccRCC) remain poorly understood. Here...

Anesthesia TeleConsultation for Pediatric preoperative assessment: a large national prospective multicentric study in children (TeleCCCAP)

Background: While interest in pediatric anesthesia teleconsultation is growing, published data remain scarce. This study evaluated the feasibility of anesthesia teleconsultation in children, providing a comprehensive analysis of failure, quality, dedicated time and satisfaction....

Use of cardiac magnetic resonance imaging after hospitalization for acute heart failure: insights from the French nationwide OFICA-2 cohort

Abstract Background Cardiac magnetic resonance (CMR) has a central role in the management of patients with acute heart failure (AHF), but timely access remains heterogeneous. We investigated real-world CMR use in patients hospitalized for AHF and its associations with demographic...