Centre Hospitalier Régional et Universitaire de Nancy

Longitudinal progression, metrics, age-dependence, and modifiers of ataxia severity in SCA27B: a multicentre study of 219 patients

Background Spinocerebellar Ataxia 27B (SCA27B) is a novel, frequent and likely treatable late-onset autosomal-dominant ataxia caused by GAA repeat-expansions in FGF14 . For understanding disease evolution and imminent trial planning, metrics of the most widely used clinical outco...

Current Use, Monitoring and Reversal of Neuromuscular Block in Pediatric Anesthesia and Intensive Care: A Web‐Based Cross‐Sectional ESAIC Survey

BACKGROUND: Neuromuscular blocking agents are recommended by the European Society of Anaesthesiology and Intensive Care (ESAIC) and European Society of Paediatric Anaesthesia (ESPA) for facilitating tracheal intubation in children. Despite these recommendations, real-world data o...

The Challenge of Adapting a Spatial Accessibility Indicator Developed for Primary Care to the Hemodialysis Context

Background: Access to dialysis facilities greatly affects patients' quality of life and healthcare costs. Transportation alone represents 21% of dialysis-related expenses. Going beyond a simple focus on access, this study aimed to evaluate dialysis care accessibility in France by...

Adipose tissue and myosteatosis measured by artificial intelligence as a predictor of overall survival in bladder cancer

Body composition may influence outcomes in muscle-invasive bladder cancer (MIBC), but its prognostic role remains unclear. In particular, the impact of adipose tissue distribution and muscle quality beyond BMI has been insufficiently studied. This study aimed to evaluate whether...