Centre for Chronic Disease Control

A Multi-Stage Deep Learning Framework for Daily PM2.5 Estimation at 100 m Resolution Across the Contiguous United States, 2000–2024 (A Quarter Century of Data)

Abstract Accurate high-resolution estimation of fine particulate matter (PM2.5) remains challenging because of sparse monitoring networks and missing satellite observations. We developed a multistage deep learning framework to generate daily PM2.5 concentrations at 100 m resoluti...

Bardoxolone methyl exerts an inhibitory effect on respiratory syncytial virus infection by downregulating IL-6 via the IKKβ/NF-κB signaling pathway

ABSTRACT Respiratory syncytial virus (RSV) causes severe lower respiratory tract infections in infants, older adults, and immunocompromised individuals, but therapeutic options for active infection remain limited. Interleukin-6 (IL-6) contributes to RSV replication and RSV-induce...