Centre for Cellular and Molecular Biology

Terminator-dependent facilitated recycling of RNA polymerase III provides gene-specific transcriptional activation in vivo

Genes transcribed by the RNA polymerase (Pol) III of yeast are mostly found at sites of high transcription, genomic fragility, and replication fork stalling. Transcription terminator–dependent facilitated recycling of Pol III on naked DNA templates boosts transcription in vitro;...

Antibiotic development and a path to access in India

Antibiotic development has historically been concentrated in high-income countries. We discuss how India is emerging as an important centre for antimicrobial development, and the implications for global health and equity of access to life-saving therapies. India is emerging as an...