Institution
Centre d'Immunologie et des Maladies Infectieuses
Recent research
- Health & MedicineOpen access
Does infection progression of Mycobacterium abscessus depend on sex, age, and mouse strain?
ABSTRACT The lack of a reliable chronic murine model limits drug evaluation against Mycobacterium abscessus . Existing models show discrepancies, especially regarding host factors such as mouse strain, sex, and age. To address this issue, we compared infection establishment and p...
- Health & MedicineOpen access
The Mycobacterium avium complex (MAC) comprises genetically close nontuberculous mycobacteria responsible for human and animal infections worldwide. Increasing availability of whole-genome sequencing (WGS) data offers new opportunities for genomic surveillance and lineage trackin...
- BiologyOpen access
Antibody-mediated immune surveillance as an organizing axis of gut microbiota structure
Abstract Background The symbiotic interplay between the immune system and the endogenous microbiome is essential for maintaining homeostasis. However, most microbiome research focuses primarily on associations between disease and microbial composition, often overlooking host–micr...
- Health & MedicineOpen access
Tumor-infiltrating tissue-resident memory (TRM)-like CD8+ T cells correlate with positive prognosis and better responses to cancer immunotherapy, yet the mechanisms underlying their specification remain ill-understood. Here, we use the KP (KrasG12D, p53-/-) mouse model of lung ad...