Centre de Recherche en Neurosciences de Lyon

Weighting of Spectral and Temporal Cues with n-of-m Cochlear Implant Strategies Depends on Voice Pitch

Abstract Purpose The relative contributions of spectral and temporal cues to voice pitch perception in cochlear implant (CI) users remain unclear. This study aimed to directly quantify these contributions in dynamic speech stimuli with clinical n -of- m processors. Methods Fundam...

MRI Characteristics of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease

Importance Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a demyelinating disease distinct from multiple sclerosis (MS) and aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (AQP4+NMOSD). Magnetic resonance imaging (MRI) is central t...

Serum GFAP and Age Accurately Distinguish AQP4 ‐ IgG Positive and Double Seronegative NMOSD From MOGAD After a Recent Attack

BACKGROUND: Serum neurofilament-light chain (sNfL) and glial fibrillary acidic protein (sGFAP) are associated with multiple sclerosis (MS) activity. This study aimed to identify patient- and disease-level determinants of sNfL and sGFAP and to evaluate their ability to support dif...

Low intensity transcranial electrical stimulation for schizophrenia: a triple-blind, randomized, sham-controlled multicenter trial (STIM’Zo)

Persistent symptoms in schizophrenia remain a major therapeutic challenge. Noninvasive electrical stimulation such as transcranial random noise stimulation (tRNS) may alleviate auditory hallucinations and negative symptoms, although existing evidence is limited to case reports an...

SLC7A6OS Founder Mutation: A Rare Cause of Progressive Myoclonus Epilepsy Dated to 1100 Years Ago

BACKGROUND: SLC7A6OS c.191A>G is a rare, autosomal recessive cause of progressive myoclonus epilepsy (PME). The c.191A>G variant, first discovered in two families from Türkiye and Portugal, was recently identified in three additional probands from the USA, all of Puerto Rican anc...

Silent signals: how bodily cues and age influence speech adaptation

Abstract Do real-time visual cues of listening effort and expectations on the listener's perceived age drive speech adaptations? In experiment 1, young adults read sentences to a listener shown via a head-mounted display. Participants were told their voices were heard under noisy...

Coupling between statistical learning and interference suppression

Abstract In an ever-changing environment, synchronizing automatic and controlled behaviors is essential for successful adaptation. Yet, the relationship between these behaviors is often debated, partly because of the diverse approaches used to investigate them. The present study...

Frequency and laminar profile of feature-specific visual activity revealed by interleaved EEG–fMRI

Abstract The role of cortical oscillations in brain function has been extensively debated, resulting in a variety of theoretical frameworks. Using inter-leaved simultaneous EEG-fMRI, we examined the layer-specific relationship between oscillatory activity and visual processing. W...

Longitudinal evidence for decreasing statistical learning abilities across childhood

Abstract Statistical learning enables us to identify patterns in our environment and predict future events, thereby supporting a range of motor, cognitive, and linguistic skills. Despite its significance, the developmental trajectory of statistical learning has remained unclear d...

No gender differences in predictive processing

Abstract Statistical learning, defined as the implicit extraction of environmental regularities, is considered a fundamental cognitive mechanism that supports predictive processing across individuals, domains, and species. However, whether it is modulated by gender remains unclea...