Centre de Recherche en Cancérologie et Immunologie Intégrée Nantes Angers

Evolution of organ failures in allogeneic hematopoietic cell transplantation recipients admitted to the intensive care unit

The prognosis of allogeneic hematopoietic cell transplantation (HCT) recipients admitted to the intensive care unit (ICU) has been historically poor and a time-limited ICU trial may be considered in these patients with uncertain outcomes. How the evolution of organ failures over...

Changes in students’ self-perceived interprofessional collaborative skills following participation in the student health service program

Interprofessional collaboration is recognized as a key component of effective healthcare systems. In France, the Student Health Service (SHS) is the only mandatory and universal interprofessional training experience in health curricula. However, evidence regarding its impact on i...

Beta Atlas: Charting Global Production of Nonconventional β − -Emitters for Targeted Radiopharmaceutical Therapy—Part 1

β-minus particle (β−)–emitting radionuclides have long been central to targeted radiopharmaceutical therapy. Interest in expanding their repertoire beyond conventional options has grown over time, as the need for radionuclides with different emission profiles and theranostic pote...

Daratumumab in Combination With High‐Dose Cytarabine and Amsacrine as an Effective Salvage Therapy and Bridge to Allogeneic Hematopoietic Stem Cell Transplantation for Refractory T‐Cell Acute Lymphoblastic Leukemia: A Case Report

ABSTRACT Patients with refractory or relapsed T‐cell acute lymphoblastic leukemia (R/R T‐ALL) have dismal outcomes. While immunotherapies are growing opportunities for B‐cell ALL, targeted therapies for T‐ALL remain limited. The CD38 antigen, steadily expressed on T‐ALL blasts, r...

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

ABSTRACT The prevalence of antimicrobial resistance (AMR) within the common bacterial pathogen Streptococcus pneumoniae makes it a priority for the development of new antibiotics. While artificial intelligence (AI) has recently boosted phenotype‐based repurposing of drugs for oth...

Describing the emotional change experienced by patients with chronic somatic diseases who took part in a supportive program with complementary therapies: a qualitative study

Quantitative studies have suggested that complementary therapies (including mind-body and art therapies) are relevant to support patients with chronic somatic diseases. The “Health Promotion Education” department of Nantes University Hospital created in 2012 an association entitl...

Non-invasive multiparametric characterization of essential thrombocythemia, premyelofibrosis, and overt myelofibrosis

Among myeloproliferative neoplasms (MPN), prefibrotic myelofibrosis (preMF) was defined as a distinct entity from essential thrombocythemia (ET) and primary overt myelofibrosis (PMF) since the 2016 revision of the World Health Organization (WHO) classification, while precise char...