Central University of Tamil Nadu

Microplastics and Human Health: Exposure Pathways, Contributive Roles, and Mitigation Strategies

The sophistication of human life with the inventions and infrastructure development that followed the industrial revolution has one unintended consequence—plastic pollution. Their exponential growth, accumulation in all the environmental systems, persistence and low rate of decay...

Hydrogel‐Based Mechano‐Immunomodulation in Bone Fracture Healing: Mechanical Regulation of Macrophage Phenotypes, Osteoimmune Interactions, and Regeneration

Bone fracture healing is a meticulously regulated process encompassing the inflammatory, reparative, and remodelling phases. Macrophages serve as pivotal coordinators within this cascade, with their polarisation from pro-inflammatory M1 to proregenerative M2 phenotypes, which pla...

Integrated Effects of Digestion Strategy and LC Gradient Architecture Define Host Cell Protein Detectability in CHO Null Harvests

Abstract Accurate characterization of host cell proteins (HCPs) is critical for biologics development, yet analytical outcomes are strongly influenced by the digestion strategy and chromatographic design. Here, we systematically evaluated digestion parameters, including digestion...