Central University of Ecuador

Description of a new species of Ixodes Latreille, 1795 (Acari: Ixodidae) parasitizing small mammals in the Andean Chocó Biosphere Reserve of Ecuador

Ixodes is the most diverse genus of hard ticks worldwide, with nearly 62 species recorded in the Neotropical region, including nine in Ecuador. However, the diversity of this genus in the Ecuadorian Andean Chocó remains poorly understood. In this study, we describe a new species...

Long-Term Aesthetic Performance of Freehand Direct Anterior Composite Resin Restorations: A Systematic Review and Meta-Analysis of Colour Alteration, Marginal Discolouration, and Surface-Quality Deterioration

Background: Freehand direct composite resin veneers offer a minimally invasive approach for managing aesthetic alterations in anterior teeth; however, their long-term colour alteration and surface performance remain uncertain. This systematic review evaluated colour alteration, m...

The Human Labial Superficial Musculoaponeurotic System (SMAS): Anatomy, Imaging, and Biomechanical and Sensory Implications—A Narrative Review

The superficial musculoaponeurotic system (SMAS) is a fundamental concept in facial anatomy and surgery, but its organization within the human lips remains incompletely defined. This narrative review critically reassesses the anatomical evidence for a labial SMAS and its regional...

Condyle-preserving lateral arthroplasty for fibro-osseous temporomandibular joint ankylosis using customized cutting guides: a case report

Abstract Background Temporomandibular joint ankylosis causes progressive restriction of mandibular movement and is primarily managed surgically, although the need for routine condylar resection remains controversial. Virtual surgical planning and patient-specific cutting guides m...

CRISPR-Based Mediated Reactivation of Fetal Hemoglobin as a Therapeutic Strategy for Hemoglobinopathies: Evidence from Preclinical to Clinical Trials in Sickle Cell Disease and β-Thalassemia

β-Hemoglobinopathies, including sickle cell disease (SCD) and β-thalassemia, are inherited disorders caused by mutations in the β-globin gene (HBB), leading to defective production of adult hemoglobin (HbA), vaso-occlusive crises, and rapid destruction of erythrocytes as they lea...

INTELIGENT VIRTUAL ASSISTANT FOR UNIVERSITY GARDEN

Building smart territories faces challenges for more efficient services and facilities, as well as supporting the intelligent development of the tourism industry in terms of data analysis and prediction, automation and intelligence, personalization and customization, intelligent...

Ocular manifestations of expanded dengue syndrome: a systematic review with meta-analysis

Ocular manifestations are under-recognized complications of expanded dengue syndrome, with no robust frequency estimates available. A systematic review was conducted following PRISMA guidelines. Primary studies reporting the frequency of ocular manifestations consistent with expa...

Antimicrobial resistance in Ecuador: A One Health situational analysis of governance, infrastructure, and equity gaps

Abstract Antimicrobial resistance (AMR) represents a growing global public health threat, undermining therapeutic efficacy and disproportionately affecting vulnerable populations. In Ecuador, the situation is exacerbated by weak surveillance systems and fragmentation among the hu...

Two-Stage Conservative Management of Mandibular Unicystic Ameloblastoma with an Intraluminal Pattern: A Case Report

Intraluminal unicystic ameloblastoma is characterized by tumor proliferation confined to the cystic lumen, without invasion of the supporting connective tissue, a feature that has led some authors to regard it as particularly suited to conservative surgical treatment. Objective:...

Valorisation of Zingiber officinale hydrodistillation residual cake as a sustainable source of bioactive gingerols and shogaols: Quantification by validated HPLC-DAD and multi-spectroscopic characterization

Zingiber officinale Roscoe (ginger) hydrodistillation for essential oil production generates large quantities of residual cake, an underutilized by-product rich in non-volatile phenolics. This study characterized and quantified gingerols and shogaols in fresh Ecuadorian ginger rh...